Observational studyCancer medicine2022
Venous thromboembolism and radiation therapy: The final radiation-induced thrombosis study analysis.
Observational study in Cancer medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02696447 (Radiation Therapy and Venous Thromboembolic Events), which is not on this map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Radiation Therapy and Venous Thromboembolic Events
Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- The risk of sinus vein thrombosis in patients treated with intraoperative radiotherapy for sinus adjacent tumours.Journal of neuro-oncology · 2026Article
- Chemo-/radiotherapy-induced cardiomyopathy: roles of mitochondria and endoplasmic reticulum.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026Review
- Radiotherapy-the not-so-insignificant contributor to cancer-associated venous thrombosis.Research and practice in thrombosis and haemostasis · 2025Review
- Phlegmasia cerulea dolens as a complication of radiation therapy in endometrial cancer: a case report.AJOG global reports · 2025Article
- Development and validation of a prediction model for VTE risk in gastric and esophageal cancer patients.Frontiers in pharmacology · 2025Article
- Cancer-associated thoracic aorta arterial thrombosis: case report and review of the literature.Frontiers in cardiovascular medicine · 2025Article
- Thrombotic Complications in Pediatric Cancer.Children (Basel, Switzerland) · 2024Review
- Baseline DSB repair prediction of chronic rare Grade ≥ 3 toxicities induced by radiotherapy using classification algorithms.Journal of radiation research · 2024Article
- Late venous thromboembolism in survivors of adolescent and young adult cancer: A population-based study in California.Thrombosis research · 2024Article
- Incidence of venous thromboembolism following head and neck surgery.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Article
- Venous thromboembolism in Japanese patients with breast cancer: subgroup analysis of the Cancer-VTE Registry.Breast cancer (Tokyo, Japan) · 2023Observational
- [Incidence and Risk Factors of Venous Thromboembolism in Patients with Lung Adenocarcinoma Receiving Anti-tumor Therapy].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2023Article
- Article
- Venous thromboembolism and radiation therapy: The final radiation-induced thrombosis study analysis.Cancer medicine · 2022Observational
- The Efficacy of the Systemic Immune-Inflammation Index and Prognosis Nutritional Index for the Diagnosis of Venous Thromboembolism in Gastrointestinal Cancers.Journal of inflammation research · 2022Article
- Risk Factors of Venous Thromboembolism in Inpatients With Colorectal Cancer in China.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThromboembolic events frequently complicate the course of malignancy and represent a major cause of morbidity and mortality in cancer patients. In contrast to chemotherapy and other systemic therapies, little is known about the impact of ionizing radiations on the incidence of venous thromboembolism (VTE) in cancer patients.
methodsIn the present prospective study, we aimed to investigate the incidence, management, and outcome of VTE in newly diagnosed cancer patients who received curative radiotherapy.
resultsVTE was found in 8 patients, out of 401 patients at a median time of 80 days after radiotherapy initiation. The incidence rate of VTE at 6 months post-treatment was 2% (95% CI, 0.9-3.7), with 50% of cases occurring during the radiotherapy course and 50% of cases in patients who received or were receiving chemotherapy. As none of the patients harbored a personal history of VTE, no prophylactic measure was initiated during cancer therapy. Most patients received monotherapy with low-molecular-weight heparin and were still on surveillance at the end of the study. No specific clinical risk factor was identified that might systematically indicate the need of thromboprophylaxis in the context of curative radiotherapy.
conclusionsAlthough this pan-cancer descriptive study did not relate an increased risk of short-term thrombosis following ionizing radiation, it provides important insight as a basis for future studies with subcategories of cancer, in order to in fine guide further recommendations in frail patients. CLINICAL TRIAL REGISTRATION NUMBER: NCT02696447.
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