SynthesisArtificial organs2022
Extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest: A systematic review and meta-analysis of randomized and propensity score-matched studies.
Synthesis in Artificial organs, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 8 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Neurological outcome predictors after extracorporeal cardiopulmonary resuscitation: a systematic review.Systematic reviews · 2025Pooled it
- Comparison of prognosis between extracorporeal CPR and conventional CPR for patients in cardiac arrest: a systematic review and meta-analysis.BMC emergency medicine · 2024Pooled it
- Extracorporeal cardiopulmonary resuscitation versus standard treatment for refractory out-of-hospital cardiac arrest: a Bayesian meta-analysis.Critical care (London, England) · 2024Pooled it
- Extracorporeal membrane oxygenation technology for adults: an evidence mapping based on systematic reviews.European journal of medical research · 2024Pooled it
- Extracorporeal membrane oxygenation for critically ill adults.The Cochrane database of systematic reviews · 2023Pooled it
- Pooled it
- Extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest: A systematic review and meta-analysis of randomized and propensity score-matched studies.Artificial organs · 2022Pooled it
- Double sequential external defibrillation versus standard defibrillation in refractory ventricular fibrillation: A systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2022Pooled it
- Endovascular resuscitation: an expert practice review.Emergency medicine journal : EMJ · 2026Review
- Optimizing Regional Access to Extracorporeal Cardiopulmonary Resuscitation: A Geographic-Information-System-Based Comparison of Hospital- and Prehospital-Initiated Strategies in Nara Prefecture, Japan.Healthcare (Basel, Switzerland) · 2026Article
- Long-term neurological outcome following out-of-hospital cardiac arrest in Switzerland: a single-centre observational study.Frontiers in medicine · 2025Article
- Establishing an Extracorporeal Cardiopulmonary Resuscitation Program.Medicina (Kaunas, Lithuania) · 2024Article
- Mild (34 °C) versus moderate hypothermia (24 °C) in a swine model of extracorporeal cardiopulmonary resuscitation.Resuscitation plus · 2024Article
- Extracorporeal cardiopulmonary resuscitation for patients with refractory out-of-hospital cardiac arrest: a propensity score matching, observational study.Scientific reports · 2024Observational
- Extracorporeal cardiopulmonary resuscitation for refractory out-of-hospital cardiac arrest: Lessons learned from recent clinical trials.Journal of the American College of Emergency Physicians open · 2024Review
- Extracorporeal life support in cardiac arrest: a post hoc Bayesian re-analysis of the INCEPTION trial.European heart journal. Acute cardiovascular care · 2024Article
- Extracorporeal cardiopulmonary resuscitation in 2023.Intensive care medicine experimental · 2023Review
- Benefits, key protocol components, and considerations for successful implementation of extracorporeal cardiopulmonary resuscitation: a review of the recent literature.Clinical and experimental emergency medicine · 2023Article
- Extracorporeal cardiopulmonary resuscitation for refractory OHCA: lessons from three randomized controlled trials-the trialists' view.European heart journal. Acute cardiovascular care · 2023Article
- Extracorporeal Membrane Oxygenation.Respiratory care · 2023Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn selected patients with refractory out-of-hospital cardiac arrest, extracorporeal cardiopulmonary resuscitation represents a promising approach when conventional cardiopulmonary resuscitation fails to achieve return of spontaneous circulation. This systematic review and meta-analysis aimed to compare extracorporeal cardiopulmonary resuscitation to conventional cardiopulmonary resuscitation.
methodsWe searched PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials up to November 28, 2021, for randomized trials and observational studies reporting propensity score-matched data and comparing adults with out-of-hospital cardiac arrest treated with extracorporeal cardiopulmonary resuscitation with those treated with conventional cardiopulmonary resuscitation. The primary outcome was survival with favorable neurological outcome at the longest follow-up available. Secondary outcomes were survival at the longest follow-up available and survival at hospital discharge/30 days.
resultsWe included six studies, two randomized and four propensity score-matched studies. Patients treated with extracorporeal cardiopulmonary resuscitation had higher rates of survival with favorable neurological outcome (81/584 [14%] vs. 46/593 [7.8%]; OR = 2.11; 95% CI, 1.41-3.15; p < 0.001, number needed to treat 16) and of survival (131/584 [22%] vs. 102/593 [17%]; OR = 1.40; 95% CI, 1.05-1.87; p = 0.02) at the longest follow-up available compared with conventional cardiopulmonary resuscitation. Survival at hospital discharge/30 days was similar between the two groups (142/584 [24%] vs. 122/593 [21%]; OR = 1.26; 95% CI, 0.95-1.66; p = 0.10).
conclusionsEvidence from randomized trials and propensity score-matched studies suggests increased survival and favorable neurological outcome in patients with refractory out-of-hospital cardiac arrest treated with extracorporeal cardiopulmonary resuscitation. Large, multicentre randomized studies are still ongoing to confirm these findings.
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