Evidence map›Paper›PMID 35199189›Full record

ArticleJournal of cancer research and clinical oncology2023

Analysis of online plan adaptation for 1.5T magnetic resonance-guided stereotactic body radiotherapy (MRgSBRT) of prostate cancer.

Darren M C Poon, Bin Yang, Hui Geng, Oi Lei Wong, Sin Ting Chiu, Kin Yin Cheung, Siu Ki Yu, George Chiu, Jing Yuan

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cancer research and clinical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Dosimetric evaluation of ultrafractionated dose escalation with simultaneous integrated boost to intraprostatic lesion using 1.5-Tesla MR-Linac in localized prostate cancer.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2024
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Darren M C PoonComprehensive Oncology Centre, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong, Hong Kong SAR, China. darren.mc.poon@hksh.com.ORCID http://orcid.org/0000-0002-6226-0743
Bin YangMedical Physics Department, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong, Hong Kong SAR, China.
Hui GengMedical Physics Department, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong, Hong Kong SAR, China.
Oi Lei WongResearch Department, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong, Hong Kong SAR, China.
Sin Ting ChiuDepartment of Radiotherapy, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong, Hong Kong SAR, China.
Kin Yin CheungMedical Physics Department, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong, Hong Kong SAR, China.
Siu Ki YuMedical Physics Department, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong, Hong Kong SAR, China.
George ChiuDepartment of Radiotherapy, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong, Hong Kong SAR, China.
Jing YuanResearch Department, Hong Kong Sanatorium and Hospital, Happy Valley, Hong Kong, Hong Kong SAR, China.
Hong Kong Sanatorium and Hospital · HK

Funding

Hong Kong Sanatorium and Hospital REC-2019-09
6 · The paper itself

Abstract

purposeTo analyze and characterize the online plan adaptation of 1.5T magnetic resonance-guided stereotactic body radiotherapy (MRgSBRT) of prostate cancer (PC).

methodsPC patients (n = 107) who received adaptive 1.5 Tesla MRgSBRT were included. Online plan adaptation was implemented by either the adapt-to-position (ATP) or adapt-to-shape (ATS) methods. Patients were assigned to the ATS group if they underwent ≥ 1 ATS fraction (n = 51); the remainder were assigned to the ATP group (n = 56). The online plan adaptation records of 535 (107 × 5) fractions were retrospectively reviewed. Rationales for ATS decision-making were determined and analyzed using predefined criteria. Statistics of ATS fractions were summarized. Associations of patient characteristics and clinical factors with ATS utilization were investigated.

resultsThere were 87 (16.3%) ATS fractions and 448 ATP fractions (83.7%). The numbers of ATS adoptions in fractions 1-5 were 29 (29/107, 27.1%), 18 (16.8%), 15 (14.0%), 16 (15.0%), and 9 (8.4%), respectively, with significant differences in adoption frequency between fractions (p = 0.007). Other baseline patient characteristics and clinical factors were not significantly associated with ATS classification (all p > 0.05). Underlying criteria for the determination of ATS implementation comprised anatomical changes (77 fractions in 50 patients) and discrete multiple targets (15 fractions in 3 patients). No ATS utilization was determined using dosimetric or online quality assurance criteria.

conclusionsThis study contributes to facilitating the establishment of a standardized protocol for online MR-guided adaptive radiotherapy in PC.

Indexed as

Prostatic NeoplasmsRadiosurgeryRadiotherapy, Image-GuidedAdenosine TriphosphateHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRetrospective StudiesAdenosine TriphosphateAdapt-to-position (ATP)Adapt-to-shape (ATS)Magnetic resonance guided radiotherapy (MRgRT)Online plan adaptationProstate cancer (PC)Stereotactic body radiotherapy (SBRT)

Identifiers

PMID35199189
PMCPMC8866042
OpenAlexW4213420747

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.