Evidence map›Paper›PMID 35198998›Full record

ArticleCurrent research in food science2022

Gut microbiota modulation by jabuticaba peel and its effect on glucose metabolism via inflammatory signaling.

Paulo Sérgio Loubet Filho, Andressa Mara Baseggio, Milena Morandi Vuolo, Lívia Mateus Reguengo, Aline Camarão Telles Biasoto, Luiz Claudio Correa, Stanislau Bogusz Junior, Valéria Helena Alves Cagnon, Cinthia Baú Betim Cazarin, Mário Roberto Maróstica Júnior

Abstract read
In one paragraph

Article in Current research in food science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Plants (Basel, Switzerland) · 2024
    Article
  2. Article
  3. Article
  4. Exploration of theNutrients · 2024
    Review
  5. Plants (Basel, Switzerland) · 2024
    Article
  6. Enhancing Rumen Fermentation and Bacteria Community in Sika Deer (Animals : an open access journal from MDPI · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Paulo Sérgio Loubet FilhoLaboratory of Nutrition and Metabolism, School of Food Engineering, University of Campinas - UNICAMP, P.O. Box 6121, 13083-862, Campinas, SP, Brazil.
Andressa Mara BaseggioLaboratory of Nutrition and Metabolism, School of Food Engineering, University of Campinas - UNICAMP, P.O. Box 6121, 13083-862, Campinas, SP, Brazil.
Milena Morandi VuoloLaboratory of Nutrition and Metabolism, School of Food Engineering, University of Campinas - UNICAMP, P.O. Box 6121, 13083-862, Campinas, SP, Brazil.
Lívia Mateus ReguengoLaboratory of Nutrition and Metabolism, School of Food Engineering, University of Campinas - UNICAMP, P.O. Box 6121, 13083-862, Campinas, SP, Brazil.
Aline Camarão Telles BiasotoBrazilian Agricultural Research Corporation, Embrapa Tropical Semi-arid, 56302-970, Petrolina, PE, Brazil.
Luiz Claudio CorreaBrazilian Agricultural Research Corporation, Embrapa Tropical Semi-arid, 56302-970, Petrolina, PE, Brazil.
Stanislau Bogusz JuniorSão Carlos Institute of Chemistry (IQSC), University of São Paulo (USP), São Carlos, SP, Brazil.
Valéria Helena Alves CagnonDepartment of Structural and Functional Biology, Institute of Biology, University of Campinas- UNICAMP, Bertrand Russel Av, Campinas, SP, Brazil.
Cinthia Baú Betim CazarinLaboratory of Nutrition and Metabolism, School of Food Engineering, University of Campinas - UNICAMP, P.O. Box 6121, 13083-862, Campinas, SP, Brazil.
Mário Roberto Maróstica JúniorLaboratory of Nutrition and Metabolism, School of Food Engineering, University of Campinas - UNICAMP, P.O. Box 6121, 13083-862, Campinas, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Jabuticaba is a Brazilian berry known for its therapeutic potential against cancer, obesity, insulin resistance (IR), and others. It is a natural source of bioactive compounds, leading to better glucose metabolism, and attenuating obesity and IR through the reduction of pro-inflammatory status. The present study aimed to observe the prebiotic effect of freeze-dried jabuticaba peel (J) consumption on gut bacteria profile and describe its effects on IR derived from the lipopolysaccharides/Toll-like receptor-4 inflammatory pathway. Jabuticaba peel was chemically characterized, and its bioactive compounds were quantified. Twenty-four C57BL/6 mice were feed with a control diet (n = 6), control diet + J (n = 6), high-fat diet (HF) (n = 6), and HF + J (n = 6) for thirteen weeks. Gut bacteriota (16s RNA sequencing), glucose metabolism (fasting glucose and insulin, OGTT, ITT, HOMA-IR, and β, QUICKI), and inflammatory status (serum lipopolysaccharide, and protein expression) were assessed. The main bioactive compounds found in J were dietary fiber, and anthocyanins, and its consumption along with a healthy diet reduced the abundance of

Indexed as

BerriesBioactive compoundsDysbiosisInsulin resistanceObesityPrebiotics

Identifiers

PMID35198998
PMCPMC8850559

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.