Evidence map›Paper›PMID 35198977›Full record

ArticleBrain communications2022

Structural and functional brain alterations in patients with myasthenia gravis.

Benita Klaus, Patrick Müller, Nora van Wickeren, Milos Dordevic, Marlen Schmicker, Yael Zdunczyk, Tanja Brigadski, Volkmar Leßmann, Stefan Vielhaber, Stefanie Schreiber and 1 more

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Does myasthenia gravis impact cognitive functioning? A systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Benita KlausGerman Centre for Neurodegenerative Diseases, 39120 Magdeburg, Germany.
Patrick MüllerGerman Centre for Neurodegenerative Diseases, 39120 Magdeburg, Germany.
Nora van WickerenGerman Centre for Neurodegenerative Diseases, 39120 Magdeburg, Germany.
Milos DordevicGerman Centre for Neurodegenerative Diseases, 39120 Magdeburg, Germany.
Marlen SchmickerGerman Centre for Neurodegenerative Diseases, 39120 Magdeburg, Germany.
Yael ZdunczykDepartment of Neurology, Otto-von-Guericke University, 39120 Magdeburg, Germany.
Tanja BrigadskiInstitute of Physiology, Otto-von-Guericke University, 39120 Magdeburg, Germany.
Volkmar LeßmannInstitute of Physiology, Otto-von-Guericke University, 39120 Magdeburg, Germany.ORCID https://orcid.org/0000-0002-6863-323X
Stefan VielhaberGerman Centre for Neurodegenerative Diseases, 39120 Magdeburg, Germany.
Stefanie SchreiberGerman Centre for Neurodegenerative Diseases, 39120 Magdeburg, Germany.ORCID https://orcid.org/0000-0003-4439-4374
Notger G MüllerGerman Centre for Neurodegenerative Diseases, 39120 Magdeburg, Germany.
German Center for Neurodegenerative Diseases · DECenter for Behavioral Brain Sciences · DEOtto-von-Guericke-Universität Magdeburg · DEUniversity of Kaiserslautern · DEUniversity of Potsdam · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myasthenia gravis is an autoimmune disease affecting neuromuscular transmission and causing skeletal muscle weakness. Additionally, systemic inflammation, cognitive deficits and autonomic dysfunction have been described. However, little is known about myasthenia gravis-related reorganization of the brain. In this study, we thus investigated the structural and functional brain changes in myasthenia gravis patients. Eleven myasthenia gravis patients (age: 70.64 ± 9.27; 11 males) were compared to age-, sex- and education-matched healthy controls (age: 70.18 ± 8.98; 11 males). Most of the patients (

Indexed as

BDNFmyasthenia gravisneuroplasticityneuropsychological testingVBM

Identifiers

PMID35198977
PMCPMC8856136
OpenAlexW4210769267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.