Evidence map›Paper›PMID 35198967›Full record

ArticleBiofilm2022

Synergistic effect of antibiotic combinations on

Ekta Kamble, Purva Sanghvi, Karishma Pardesi

Open access · goldAbstract read
In one paragraph

Article in Biofilm, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Eradication ofACS infectious diseases · 2024
    Article
  9. Review
  10. Article
  11. Article
  12. Manuka honey as a non-antibiotic alternative againstFrontiers in cellular and infection microbiology · 2024
    Review
  13. Article
  14. Combinatorial efficacy of Manuka honey and antibiotics in theFrontiers in cellular and infection microbiology · 2023
    Article
  15. Antibiofilm Activity and Synergistic Effects of Thymol-Loaded Poly (Lactic-Co-Glycolic Acid) Nanoparticles with Amikacin against FourThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
    Article
  16. Characterization of NovelMicrobiology spectrum · 2022
    Article
  17. Frontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ekta KambleDepartment of Microbiology, Savitribai Phule Pune University, Ganeshkhind Road, Pune, 411 007, Maharashtra, India.
Purva SanghviDepartment of Microbiology, Savitribai Phule Pune University, Ganeshkhind Road, Pune, 411 007, Maharashtra, India.
Karishma PardesiDepartment of Microbiology, Savitribai Phule Pune University, Ganeshkhind Road, Pune, 411 007, Maharashtra, India.
Savitribai Phule Pune University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment of staphylococcal infections is difficult due to multidrug resistance with their persister forms posing an added threat of recalcitrant infections. Antibiotic combinations are widely studied as an alternative strategy to combat them; therefore, they merit further investigation into their effect on the number of persister cells. In the present study, the fractional inhibitory concentrations of antibiotic combinations ciprofloxacin-daptomycin, ciprofloxacin-vancomycin, daptomycin-tobramycin, and tobramycin-vancomycin (checkerboard assay) were determined against two previously studied clinical (S48 and J6) and one standard (NCIM 5021) isolate of

Indexed as

BiofilmDrug combinationDrug toleranceStaphylococcus aureus

Identifiers

PMID35198967
PMCPMC8844754
OpenAlexW4210741336

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.