Evidence map›Paper›PMID 35198912›Full record

ArticleiScience2022

Longitudinal 16S rRNA gut microbiota data of infant triplets show partial susceptibility to host genetics.

Ondina Palmeira, Larissa R B Matos, Michel S Naslavsky, Heloisa M S Bueno, Júlia P Soler, João C Setubal, Mayana Zatz

Abstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Early-life microbiota-immune homeostasis.Frontiers in immunology · 2023
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ondina PalmeiraDepartment of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, SP 05508-900, Brazil.
Larissa R B MatosHuman Genome and Stem Cell Research Center, Institute of Biosciences, University of São Paulo, São Paulo, SP 05508-090, Brazil.
Michel S NaslavskyHuman Genome and Stem Cell Research Center, Institute of Biosciences, University of São Paulo, São Paulo, SP 05508-090, Brazil.
Heloisa M S BuenoHuman Genome and Stem Cell Research Center, Institute of Biosciences, University of São Paulo, São Paulo, SP 05508-090, Brazil.
Júlia P SolerDepartment of Statistics, Institute of Mathematics and Statistics, University of São Paulo, São Paulo, SP 05508-090, Brazil.
João C SetubalDepartment of Biochemistry, Institute of Chemistry, University of São Paulo, São Paulo, SP 05508-900, Brazil.
Mayana ZatzHuman Genome and Stem Cell Research Center, Institute of Biosciences, University of São Paulo, São Paulo, SP 05508-090, Brazil.

Funding

SOLAR-Eclipse Computational Tools for Imaging GeneticsR01EB015611 · NIBIB · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KOCHUNOV, PETER V. · 2012 to 2024
$5.0M
NIBIB NIH HHS R01 EB015611
6 · The paper itself

Abstract

The question of whether host genetics plays a role in the development of the infant gut microbiota does not, as yet, have a clear answer. In order to throw additional light on this question, we have analyzed 16S rRNA amplicon sequences from 99 valid fecal samples of five sets of dichorionic triplet babies born by C-section from 1 to 36 months of age. Beta diversity analysis showed that monozygotic twins were more similar to each other than their dizygotic siblings. Monozygotic twins also tended to share more amplicon sequence variants between them. Heritability analysis showed that the genera

Indexed as

MicrobiologyMicrobiome

Identifiers

PMID35198912
PMCPMC8850664

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.