ArticleiScience2022
Sex-specific divergent maturational trajectories in the postnatal rat basolateral amygdala.
Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Postnatal maturation of the basolateral and paralaminar amygdala in rodents: implications for social-emotional development.Frontiers in neuroscience · 2026Review
- Developmental Shifts in Amygdala Function.Current topics in behavioral neurosciences · 2025Review
- Cell- and Pathway-Specific Disruptions in the Accumbens of Fragile X Mouse.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Basolateral amygdala neuropeptide Y system modulates binge ethanol consumption.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Sexually Dimorphic Adolescent Trajectories of Prefrontal Endocannabinoid Synaptic Plasticity Equalize in Adulthood, Reflected by Endocannabinoid System Gene Expression.Cannabis and cannabinoid research · 2023Article
- Sex differences in pre- and post-synaptic glutamate signaling in the nucleus accumbens core.Biology of sex differences · 2023Article
- Rac1 GTPase activation impairs fear conditioning-induced structural changes in basolateral amygdala neurons and long-term fear memory formation.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Article
- Sex differences in fear responses: Neural circuits.Neuropharmacology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 2 countries.
Funding
Abstract
In rodents and humans, the basolateral amygdala (BLA), essential for emotional behaviors, is profoundly reorganized during adolescence. We compared in both sexes the morphology, neuronal, and synaptic properties of BLA neurons in rats at puberty and adulthood. BLA neurons were more excitable in males than in females at adulthood. At pubescence, male action potentials were smaller and shorter than females' while fast afterhyperpolarizations were larger in males. During postnatal maturation, spine length increased and decreased in females and males, respectively, while there was a reduction in spine head size in females. Excitatory synaptic properties, estimated from stimuli-response relationships, spontaneous post-synaptic currents, and AMPA/NMDA ratio also displayed sex-specific maturational differences. Finally, the developmental courses of long-term potentiation and depression were sexually dimorphic. These data reveal divergent maturational trajectories in the BLA of male and female rats and suggest sex-specific substrates to the BLA linked behaviors at adolescence and adulthood.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.