Evidence map›Paper›PMID 35198865›Full record

ArticleiScience2022

Amy E Clipperton-Allen, Hannah Swick, Valentina Botero, Massimiliano Aceti, Jacob Ellegood, Jason P Lerch, Damon T Page

Open access · goldAbstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Altered Primary Somatosensory Neuron Development in a Pten Heterozygous Model for Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  3. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Amy E Clipperton-AllenDepartment of Neuroscience, The Scripps Research Institute, Jupiter, FL 33458, USA.
Hannah SwickDepartment of Neuroscience, The Scripps Research Institute, Jupiter, FL 33458, USA.
Valentina BoteroDepartment of Neuroscience, The Scripps Research Institute, Jupiter, FL 33458, USA.
Massimiliano AcetiDepartment of Neuroscience, The Scripps Research Institute, Jupiter, FL 33458, USA.
Jacob EllegoodMouse Imaging Centre, Hospital for Sick Children, Toronto, ON M5T 3H7, Canada.
Jason P LerchMouse Imaging Centre, Hospital for Sick Children, Toronto, ON M5T 3H7, Canada.
Damon T PageDepartment of Neuroscience, The Scripps Research Institute, Jupiter, FL 33458, USA.
Scripps Research Institute · USHospital for Sick Children · CA

Funding

Regulation of mTOR signaling in the developing cerebral cortex as a point of convergence for multiple autism risk factorsR01MH108519 · NIMH · UNIVERSITY OF FLORIDA · PI PAGE, DAMON THERON · 2016 to 2025
$4.8M
Impact of Pten mutations on brain growth and social behavioral development.R01MH105610 · NIMH · SCRIPPS FLORIDA · PI PAGE, DAMON THERON · 2015 to 2019
$2.4M
Delineating contributions of PI3K signaling to neurodevelopmental consequences of Pten haploinsufficiencyR21NS121951 · NINDS · UNIVERSITY OF FLORIDA · PI PAGE, DAMON THERON · 2021 to 2021
$509k
NIMH NIH HHS R01 MH105610NIMH NIH HHS R01 MH108519NINDS NIH HHS R21 NS121951
6 · The paper itself

Abstract

How changes in brain scaling relate to altered behavior is an important question in neurodevelopmental disorder research. Mice with germline

Indexed as

Behavioral neuroscienceBiological sciencesImaging anatomyNeuroscienceSmall animal imaging

Identifiers

PMID35198865
PMCPMC8844819
OpenAlexW4205488604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.