Evidence map›Paper›PMID 35198838›Full record

ArticleAdvances in radiation oncology

Application of Continuous Positive Airway Pressure for Thoracic Respiratory Motion Management: An Assessment in a Magnetic Resonance Imaging-Guided Radiation Therapy Environment.

Evan Liang, Jennifer L Dolan, Eric D Morris, Jonathan Vono, Luisa F Bazan, Mei Lu, Carri K Glide-Hurst

Open access · goldAbstract read
In one paragraph

Article in Advances in radiation oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Heart is a heavy burden: cardiac toxicity in radiation oncology.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Evan LiangDepartment of Radiation Oncology, Henry Ford Health System, Detroit, Michigan.
Jennifer L DolanDepartment of Radiation Oncology, Henry Ford Health System, Detroit, Michigan.
Eric D MorrisDepartment of Radiation Oncology, Henry Ford Health System, Detroit, Michigan.
Jonathan VonoDepartment of Pulmonary and Sleep Medicine, Henry Ford Health System, Detroit, Michigan.
Luisa F BazanDepartment of Pulmonary and Sleep Medicine, Henry Ford Health System, Detroit, Michigan.
Mei LuDepartment of Radiation Oncology, Henry Ford Health System, Detroit, Michigan.
Carri K Glide-HurstDepartment of Radiation Oncology, Henry Ford Health System, Detroit, Michigan.
Henry Ford Health System · USUniversity of Wisconsin–Madison · US

Funding

Reducing cardiac toxicity with deep learning and MRI-guided radiation therapyR01HL153720 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI GLIDE-HURST, CARRI KAYE · 2021 to 2024
$2.2M
Development of Anatomical Patient Models to Facilitate MR-only Treatment PlanningR01CA204189 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI GLIDE-HURST, CARRI KAYE · 2016 to 2020
$1.5M
NCI NIH HHS R01 CA204189NHLBI NIH HHS R01 HL153720
6 · The paper itself

Abstract

purposePatient tolerability of magnetic resonance (MR)-guided radiation treatment delivery is limited by the need for repeated deep inspiratory breath holds (DIBHs). This volunteer study assessed the feasibility of continuous positive airway pressure (CPAP) with and without DIBH for respiratory motion management during radiation treatment with an MR-linear accelerator (MR-linac). METHODS AND MATERIALS: MR imaging safety was first addressed by placing the CPAP device in an MR-safe closet and configuring a tube circuit via waveguide to the magnet bore. Reproducibility and linearity of the final configuration were assessed. Six healthy volunteers underwent thoracic imaging in a 0.35T MR-linac, with one free breathing (FB) and 2 DIBH acquisitions being obtained at 5 pressures from 0 to 15 cm-H

resultsCompared with FB alone, FB-10, FB-12, and FB-15 cm H

conclusionsThis work demonstrates the feasibility of integrating CPAP in an MR-linac environment in healthy volunteers. Extending this work to a larger patient cohort is warranted to further establish the role of CPAP as an alternative and concurrent approach to DIBH in MR-guided radiation therapy.

Identifiers

PMID35198838
PMCPMC8844850
OpenAlexW4205429594

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.