ArticleAmerican journal of ophthalmology case reports2022
Risk factors, management, and outcomes of
Article in American journal of ophthalmology case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 38 citations in OpenAlex.
- Interpreting prediagnostic corticosteroid use in Acanthamoeba keratitis: corticosteroid type and inflammatory phenotype.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Prognostic factors for therapeutic keratoplasty in Acanthamoeba keratitis: a retrospective study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Article
- Current Challenges and Long-Term Outcomes in Corneal Transplantation in Infectious Keratitis-A Systematic Review.Journal of clinical medicine · 2026Review
- Corneal collagen cross-linking combined with lamellar keratoplasty in the treatment of Acanthamoeba keratitis.International ophthalmology · 2025Article
- Polihexanide (PHMB) 0.08% versus currently used treatments forBMJ open ophthalmology · 2025Observational
- Acanthamoeba Keratitis Management and Prognostic Factors: A Systematic Review.Journal of clinical medicine · 2025Review
- The Antimicrobial Efficacy of Amine-Containing Surfactants Against Cysts and Trophozoites ofMicroorganisms · 2025Article
- Outcome of photodynamic therapy with Rose Bengal in conjunction with topical PHMB and chlorhexidine combination in Acanthamoeba keratitis.Journal of ophthalmic inflammation and infection · 2025Article
- Article
- Acanthamoeba keratitis: from pathophysiology to prevention, a contemporary clinical perspective.Medical hypothesis, discovery & innovation ophthalmology journal · 2025Review
- Oxford Nanopore Technology-Based Identification of anMicroorganisms · 2024Article
- Rethinking Keratoplasty for Patients with Acanthamoeba Keratitis: Early "Low Load Keratoplasty" in Contrast to Late Optical and Therapeutic Keratoplasty.Microorganisms · 2024Article
- Review
- Assessing PCR-Positive Acanthamoeba Keratitis-A Retrospective Chart Review.Microorganisms · 2024Article
- [Bilateral chronic contact lens-associated keratitis].Die Ophthalmologie · 2024Article
- Infectious keratitis in Western New York: a 10-year review of patient demographics, clinical management, and treatment failure.Frontiers in ophthalmology · 2024Article
- Enhancing Rose Bengal penetration inTherapeutic delivery · 2024Article
- Zooming in on the intracellular microbiome composition of bacterivorousISME communications · 2024Article
- The role of naturally acquired intracellular Pseudomonas aeruginosa in the development of Acanthamoeba keratitis in an animal model.PLoS neglected tropical diseases · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate the risk factors, medical and surgical management, and visual outcomes of patients affected by OBSERVATIONS: Records were reviewed retrospectively for all AK patients treated at University of Iowa between 2002 and 2017. Main outcomes measured were risk factors, time to diagnosis, coinfection types, initial and final visual acuities, and treatment outcomes, with failure of medical therapy defined as need for therapeutic keratoplasty (TK). Effects of steroid use on these outcomes were determined. Among all AK cases occurring during the study period (N = 110), the median age of the AK cohort was 31 years (range 8-80 years), and 49.1% were men. Contact lens wear was the primary risk factor for AK (95/100, 86.4%), and the median time to diagnosis was 0.70 (0.23-1.23) months. Forty-four AK patients (40%) failed medical therapy. Vision outcomes were better for AK patients with successful medical therapy compared to those requiring TK (LogMAR 0.00 v. 0.30; p < 0.0001). Corticosteroid use was associated with increased time to diagnosis (1.00 v. 0.50 months; p = 0.002), decreased final vision (LogMAR 0.10 v. 0.00; p < 0.05) and increased need for TK (40/77 v. 4/33; p < 0.001). CONCLUSIONS AND IMPORTANCE:
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.