ArticleFrontiers in medicine2021
Effects of Carbon Dioxide and Temperature on the Oxygen-Hemoglobin Dissociation Curve of Human Blood: Implications for Avalanche Victims.
Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Influence of brief carbon dioxide inhalation on acute exercise performance and recovery: A pilot study.Physiological reports · 2026Trial
- Surgical Humidification (HumiGardGlobal spine journal · 2026Article
- Evaluation of oxygen reserve index as an early warning indicator of hypoxemia in anesthetized dogs.The Journal of veterinary medical science · 2025Article
- Modeling of Singlet Oxygen Generation and Thermal Effects During Laser-Tissue Interaction.Materials (Basel, Switzerland) · 2025Article
- Hemoglobin Oxygen Affinity Does Not Change in the Canine Model of Moderate Acute Normovolemic Hemodilution.ACS omega · 2025Article
- Sensitivity Analysis in the Problem of the Impact of an External Heat Impulse on Oxygen Distribution in Biological Tissue.Materials (Basel, Switzerland) · 2025Article
- Comparison of ROX index with modified indices incorporating heart rate, flow rate, and PaOEuropean journal of medical research · 2025Article
- Pulse oximetry in pediatric care: Balancing advantages and limitations.World journal of clinical pediatrics · 2024Article
- Hypothermia: Beyond the Narrative Review-The Point of View of Emergency Physicians and Medico-Legal Considerations.Journal of personalized medicine · 2023Review
- Review
- Prediction of high-flow nasal cannula outcomes at the early phase using the modified respiratory rate oxygenation index.BMC pulmonary medicine · 2022Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Completely avalanche-buried patients are frequently exposed to a combination of hypoxia and hypercapnia with a risk of normothermic cardiac arrest. Patients with a long burial time and an air pocket are exposed to a combination of hypoxia, hypercapnia, and hypothermia which may lead to the development of the "triple H syndrome". This specific combination has several pathophysiological implications, particularly on the cardiovascular system and oxygen transport (oxygen supply and oxygen consumption). To examine the effects on hemoglobin oxygen affinity, we investigated venous blood samples from 15 female and 15 male healthy subjects. In a factorial design of four different carbon dioxide partial pressure (PCO
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Registered trials
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