Evidence map›Paper›PMID 35198543›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Metabolic Engineering of

Hai-Yun Gao, Huan Zhao, Tian-Yuan Hu, Zhou-Qian Jiang, Meng Xia, Yi-Feng Zhang, Yun Lu, Yuan Liu, Yan Yin, Xiao-Chao Chen and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Microbial Metabolism: Primary and Secondary Metabolites.Progress in molecular and subcellular biology · 2026
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 1 country.

Hai-Yun GaoSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Huan ZhaoSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Tian-Yuan HuSchool of Pharmacy, College of Medicine, Hangzhou Normal University, Hangzhou, China.
Zhou-Qian JiangSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Meng XiaSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Yi-Feng ZhangBeijing Shijitan Hospital, Capital Medical University, Beijing, China.
Yun LuSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Yuan LiuSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Yan YinSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China.
Xiao-Chao ChenSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Yun-Feng LuoSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Jia-Wei ZhouCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China.
Jia-Dian WangSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Jie GaoSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Wei GaoSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Lu-Qi HuangState Key Laboratory Breeding Base of Dao-di Herbs, National Resource Center for Chinese Materia Medica, Chinese Academy of Chinese Medical Sciences, Beijing, China.
Capital Medical University · CNBeijing Shijitan Hospital · CNBeijing University of Chinese Medicine · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNHangzhou Normal University · CNZhejiang University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Friedelin, the most rearranged pentacyclic triterpene, also exhibits remarkable pharmacological and anti-insect activities. In particular, celastrol with friedelin as the skeleton, which is derived from the medicinal plant

Indexed as

CRISPR/Cas9engineered strainfriedelingenomeoptimized mediumSaccharomyces cerevisiaetriterpenes

Identifiers

PMID35198543
PMCPMC8859104
OpenAlexW4210664199

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.