Evidence map›Paper›PMID 35198414›Full record

ArticleCase reports in women's health2022

Investigating a clinically actionable

R Silva, B Moran, S Das, N Mulligan, M Doughty, A Treacy, K Sheahan, C M Kelly, A G Duffy, A S Perry and 1 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in women's health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

R SilvaCancer Biology and Therapeutics Laboratory, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.
B MoranDepartment of Pathology, St Vincent's University Hospital, Dublin, Ireland.
S DasSchool of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.
N MulliganDepartment of Pathology, Mater Misericordiae University Hospital, Dublin, Ireland.
M DoughtyDepartment of Pathology, Mater Misericordiae University Hospital, Dublin, Ireland.
A TreacyDepartment of Pathology, Mater Misericordiae University Hospital, Dublin, Ireland.
K SheahanDepartment of Pathology, St Vincent's University Hospital, Dublin, Ireland.
C M KellyDepartment of Oncology, Mater Misericordiae University Hospital, Dublin, Ireland.
A G DuffyDepartment of Oncology, Mater Misericordiae University Hospital, Dublin, Ireland.
A S PerryCancer Biology and Therapeutics Laboratory, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland.
D J BrennanSystems Biology Ireland, UCD School of Medicine, University College Dublin, Dublin, Ireland.
Mater Misericordiae University Hospital · IESt. Vincent's University Hospital · IEUniversity College Dublin · IENational Maternity Hospital · IERoyal College of Surgeons in Ireland · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low-grade serous ovarian cancer (LGSOC) poses a specific clinical challenge due to advanced presentation at diagnosis and the lack of effective systemic treatments. The aim of this study was to use a precision medicine approach to identify clinically actionable mutations in a patient with recurrent LGSOC. Primary, metastatic and recurrence tissue, and blood samples were collected from a stage IV LGSOC patient. Single-gene testing for clinically actionable mutations (

Indexed as

Cell-free circulating DNADigital droplet PCRLow-grade serous ovarian cancerNext-generation sequencingTargeted therapy

Identifiers

PMID35198414
PMCPMC8851090
OpenAlexW4210636185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.