Evidence map›Paper›PMID 35198221›Full record

ArticleOxford medical case reports2022

A large amount of microscopic precipitates are inevitably injected during infusion therapy without an in-line filter.

Shinya Shimoyama, Daisuke Takahashi, Syuhei Arai, Yuji Asami, Kimiko Nakajima, Kentaro Ikeda, Takumi Takizawa, Tomio Kobayashi

Abstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shinya ShimoyamaDepartment of Pediatric Cardiology, Gunma Children's Medical Center, Shibukawa 377-8577, Japan.ORCID https://orcid.org/0000-0003-2225-9788
Daisuke TakahashiDepartment of Pharmacy, Gunma Children's Medical Center, Shibukawa 377-8577, Japan.
Syuhei AraiDepartment of Pediatric Cardiology, Gunma Children's Medical Center, Shibukawa 377-8577, Japan.
Yuji AsamiDepartment of Pediatric Cardiology, Gunma Children's Medical Center, Shibukawa 377-8577, Japan.
Kimiko NakajimaDepartment of Pediatric Cardiology, Gunma Children's Medical Center, Shibukawa 377-8577, Japan.
Kentaro IkedaDepartment of Pediatric Cardiology, Gunma Children's Medical Center, Shibukawa 377-8577, Japan.
Takumi TakizawaDepartment of Pediatrics, Graduate School of Medicine, Gunma University, Maebashi 371-8511, Japan.
Tomio KobayashiDepartment of Pediatric Cardiology, Gunma Children's Medical Center, Shibukawa 377-8577, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infusion route problems can have a significant impact on hemodynamics in children with severe heart failure. Here, we report the case of a 13-year-old girl with dilated cardiomyopathy. Her condition fluctuated due to frequent occlusion of the central venous catheter (CVC) route. However, a quick check revealed no apparent abnormalities in the CVC, infusion route, in-line filter or infusion pump. Scanning electron microscopy revealed that dobutamine and heparin had crystallized and that the in-line filter membrane was occluded. This case emphasizes the importance of proper infusion route management in pediatric patients with severe heart failure. Even drugs that are used daily may form microscopic crystals at several concentrations and administration rates. Without an in-line filter, microscopic particles are injected into the body, and there is no evidence that the injected crystals do not cause permanent damage.

Identifiers

PMID35198221
PMCPMC8858388

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.