ArticleAnnals of medicine and surgery (2012)2022
Leukoencephalopathy due to inhalational and trans-conjunctival heroin abuse: First case report from Pakistan.
Article in Annals of medicine and surgery (2012), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors at 2 institutions in 1 country.
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Abstract
introductionand importance: Heroin-induced leukoencephalopathy (HLE) is a rare illness that causes diffuse white matter destruction, leading to acute or subacute development of neurological signs and symptoms. Physicians must be aware of the likely clinical presentation to properly evaluate and diagnose this clinical entity. CASE PRESENTATION: We report the case of a young gentleman who presented with acute stupor following his first instance of heroin vapor inhalation. He later confessed to CLINICAL DISCUSSION: Leukoencephalopathy with heroin is mostly observed after inhalation (i.e., "chasing the dragon") but other routes of abuse have also been reported. Although a large spectrum of presentations exists, altered mental status, cerebellar dysfunction and fecal/urinary incontinence are the most commonly seen presenting features. Anti-oxidant therapy has shown promising results in terms of treatment.
conclusionThe growing rates of opioid use disorders require physicians to be aware of and counsel the patients regarding dangerous neurological sequelae of these drugs.
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