Evidence map›Paper›PMID 35198097›Full record

ArticleOxidative medicine and cellular longevity2022

TNF-

Yang Zhang, Weidong Jin, Dongyun Zhang, Changhai Lin, Haiyan He, Fengxin Xie, Lixia Gan, Weiling Fu, Lixiang Wu, Yongzhong Wu

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yang ZhangDepartment of Laboratory Medicine, Chongqing University Cancer Hospital, Chongqing, China.ORCID https://orcid.org/0000-0002-4061-4408
Weidong JinDepartment of Laboratory Medicine, First Affiliated Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Dongyun ZhangDepartment of Laboratory Medicine, First Affiliated Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Changhai LinDepartment of Laboratory Medicine, Chongqing University Cancer Hospital, Chongqing, China.
Haiyan HeDepartment of Laboratory Medicine, First Affiliated Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Fengxin XieDepartment of Laboratory Medicine, First Affiliated Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Lixia GanDepartment of Biochemistry and Molecular Biology, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Weiling FuDepartment of Laboratory Medicine, First Affiliated Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Lixiang WuDepartment of Laboratory Medicine, Chongqing University Cancer Hospital, Chongqing, China.ORCID https://orcid.org/0000-0003-0157-6207
Yongzhong WuDepartment of Radiotherapy, Chongqing University Cancer Hospital, Chongqing, China.ORCID https://orcid.org/0000-0001-8367-3347
Army Medical University · CNChongqing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proinflammatory cytokines play a causal role in the development of hyperinsulinemia and T2MD. FOXO1, a transcription factor which is known to enhance proinflammation, was recently shown to be involved in obesity-induced

Indexed as

AnimalsApoptosisCell LineCell SurvivalForkhead Box Protein O1Gene Expression RegulationGlucoseInsulinInsulin-Secreting CellsInsulin SecretionIslets of LangerhansJanus Kinase 2LeptinNerve Tissue ProteinsRatsReceptors, LeptinForkhead Box Protein O1Foxo1 protein, ratGlucoseInsulinJak2 protein, ratJanus Kinase 2LeptinNerve Tissue ProteinsReceptors, LeptinStat3 protein, ratSTAT3 Transcription FactorTumor Necrosis Factor-alpha

Identifiers

PMID35198097
PMCPMC8860543
OpenAlexW4213105341

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.