Evidence map›Paper›PMID 35198059›Full record

ArticleTheranostics2022

PPAR-γ integrates obesity and adipocyte clock through epigenetic regulation of

Shuai Wang, Yanke Lin, Lu Gao, Zemin Yang, Jingpan Lin, Shujing Ren, Feng Li, Jing Chen, Zhigang Wang, Zhiyong Dong and 2 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it, 105 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
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  11. Article
  12. Antiobesity Potential of Selected Latin American Edible Plants: A Review.Plant foods for human nutrition (Dordrecht, Netherlands) · 2026
    Review
  13. Review
  14. Article
  15. Article
  16. Circadian clock and cancer.Military Medical Research · 2026
    Review
  17. Review
  18. Article
  19. Article
  20. Review

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Shuai WangInstitute of molecular rhythm and metabolism, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Yanke LinInstitute of molecular rhythm and metabolism, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Lu GaoInstitute of molecular rhythm and metabolism, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Zemin YangInstitute of molecular rhythm and metabolism, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Jingpan LinInstitute of molecular rhythm and metabolism, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Shujing RenInstitute of molecular rhythm and metabolism, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Feng LiInstitute of molecular rhythm and metabolism, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Jing ChenCollege of Pharmacy, Jinan University, Guangzhou 510632, China.
Zhigang WangThe First Affiliated Hospital of Jinan University, Guangzhou 510632, China.
Zhiyong DongThe First Affiliated Hospital of Jinan University, Guangzhou 510632, China.
Pinghua SunCollege of Pharmacy, Jinan University, Guangzhou 510632, China.
Baojian WuInstitute of molecular rhythm and metabolism, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Jinan University · CNFirst Affiliated Hospital of Jinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While growing evidence suggests that circadian clock and obesity are intertwined, the underlying mechanism is poorly understood. Here, we investigate how circadian clock is linked to obesity.

Indexed as

ARNTL Transcription FactorsCLOCK ProteinsAcetyl Coenzyme AAdipocytesAnimalsCircadian RhythmEpigenesis, GeneticGene Expression RegulationGlutamineHumansMethionineMiceObesityPPAR gammaAcetyl Coenzyme AARNTL Transcription FactorsCLOCK ProteinsGlutamineMethioninePPAR gammaBMAL1circadian clockobesityPPAR-γSLC1A5

Identifiers

PMID35198059
PMCPMC8825584
OpenAlexW4206209831

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.