Evidence map›Paper›PMID 35197971›Full record

ArticleFrontiers in immunology2022

Deep Immune Phenotyping and Single-Cell Transcriptomics Allow Identification of Circulating TRM-Like Cells Which Correlate With Liver-Stage Immunity and Vaccine-Induced Protection From Malaria.

Andrés Noé, Mehreen S Datoo, Amy Flaxman, Mohammad Ali Husainy, Daniel Jenkin, Duncan Bellamy, Rebecca A Makinson, Richard Morter, Fernando Ramos Lopez, Jonathan Sheridan and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Article
  3. Tissue-resident memory CD8Nature reviews. Gastroenterology & hepatology · 2025
    Review
  4. Review
  5. Article
  6. Early Activation of Lung CD8Pathogens & immunity · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Andrés NoéThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Mehreen S DatooThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Amy FlaxmanThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Mohammad Ali HusainyDepartment of Radiology, John Radcliffe Hospital, Oxford, United Kingdom.
Daniel JenkinThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Duncan BellamyThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Rebecca A MakinsonThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Richard MorterThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Fernando Ramos LopezThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Jonathan SheridanThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Dimitrios VoukantsisBioinformatics Hub, Department of Oncology, University of Oxford, Oxford, United Kingdom.
Naveen PrasadBioinformatics Hub, Department of Oncology, University of Oxford, Oxford, United Kingdom.
Adrian V S HillThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Katie J EwerThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Alexandra J SpencerThe Jenner Institute, University of Oxford, Oxford, United Kingdom.
Jenner Institute · GBUniversity of Oxford · GBJohn Radcliffe Hospital · GB

Funding

Department of HealthMedical Research Council MR/R015236/1
6 · The paper itself

Abstract

Protection from liver-stage malaria requires high numbers of CD8+ T cells to find and kill

Indexed as

AnimalsCD8-Positive T-LymphocytesGenetic VectorsHepatocytesHumansImmunity, CellularImmunologic MemoryLiverMalariaMalaria VaccinesPlasmodiumSporozoitesTranscriptomeVaccinationMalaria Vaccinescorrelates of protection (CoP)malaria vaccinemalaria vaccine decelopmentscRNA seqtissue resident memory CD8+ T cellstissue resident memory T cellTRM

Identifiers

PMID35197971
PMCPMC8859435
OpenAlexW4210548322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.