Evidence map›Paper›PMID 35197860›Full record

ArticleFrontiers in physiology2021

Differential Effects of Exercise Programs on Neuregulin 4, Body Composition and Cardiometabolic Risk Factors in Men With Obesity.

Ayoub Saeidi, Sevda R Shishvan, Mohammad Soltani, Fatemeh Tarazi, Patricia K Doyle-Baker, Shahnaz Shahrbanian, Shirin S Mollabashi, Nikoo Khosravi, Ismail Laher, Terence A Moriarty and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. New Discovered Adipokines Associated with the Pathogenesis of Obesity and Type 2 Diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 11 institutions in 5 countries.

Ayoub SaeidiDepartment of Physical Education and Sport Sciences, Faculty of Humanities and Social Sciences, University of Kurdistan, Sanandaj, Iran.
Sevda R ShishvanDepartment of Physical Education and Sport Science, Islamic Azad University, Tehran, Iran.
Mohammad SoltaniDepartment of Biological Sciences in Sport, Faculty of Sports Sciences and Health, Shahid Beheshti University, Tehran, Iran.
Fatemeh TaraziDepartment of Exercise Physiology, Faculty of Physical Education, Alzahra University, Tehran, Iran.
Patricia K Doyle-BakerHuman Performance Lab, Faculty of Kinesiology, University of Calgary, Calgary, AB, Canada.
Shahnaz ShahrbanianDepartment of Sports Sciences, Faculty of Humanities, Tarbiat Modares University, Tehran, Iran.
Shirin S MollabashiFaculty of Sport Sciences, Atatürk University, Erzurum, Turkey.
Nikoo KhosraviDepartment of Exercise Physiology, Faculty of Physical Education, Alzahra University, Tehran, Iran.
Ismail LaherDepartment of Anesthesiology, Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
Terence A MoriartyDepartment of Exercise and Sport Science, Coastal Carolina University, Conway, SC, United States.
Kelly E JohnsonDepartment of Exercise and Sport Science, Coastal Carolina University, Myrtle Beach, SC, United States.
Trisha A VanDusseldorpDepartment of Exercise & Sport Management, Kennesaw State University, Kennesaw, GA, United States.
Hassane ZouhalLaboratoire Mouvement, Sport, Santé - EA 1274, University Rennes, Rennes, France.
Alzahra University · IRCoastal Carolina University · USAtatürk University · TRIslamic Azad University, Tehran · IRKennesaw State University · USShahid Beheshti University · IRTarbiat Modares University · IRUniversité Rennes 2 · FRUniversity of British Columbia · CAUniversity of Calgary · CAUniversity of Kurdistan · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeuregulin 4 (Nrg4) is an adipokine that is sensitive to energy expenditure and with a potential role in metabolic homeostasis and obesity. This study examined the effects of 12 weeks of three different exercise training protocols on Nrg4 levels, cardiometabolic risk factors, and body composition parameters in men with obesity.

methodsSixty adult men with obesity (Mean ± SD; age: 27.60 ± 8.4 yrs.; height: 168.4 ± 2.6 cm; weight: 96.7 ± 7.2 kg) were randomly allocated into four equal (

resultsThere were significant differences between the groups in fat-free mass (FFM), (effect size (ES): 0.78), fat mass (ES: 0.86), VO

conclusionOur results suggest that HIIT and CRT protocols have greater effects than MICT protocol on Nrg4 levels, metabolic and cardiovascular risk factors, and body composition variables in men with obesity.

Indexed as

exerciseHIIT (High Intensity Interval Training)neuregulin 4 (Nrg4)obesityresistance exercise and aerobic exercise

Identifiers

PMID35197860
PMCPMC8859436
OpenAlexW4210811988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.