ArticleFrontiers in neuroscience2022
Not Only in Sensorimotor Network: Local and Distant Cerebral Inherent Activity of Chronic Ankle Instability-A Resting-State fMRI Study.
Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Connectomic Mapping of Chronic Musculoskeletal Pain: Neural Circuitries Identified Through a Systematic Review and ALE Meta-Analysis.Neural plasticity · 2026Pooled it
- Alterations in corticospinal excitability in individuals with ankle sprains: a systematic review of transcranial magnetic stimulation studies.Frontiers in physiology · 2026Pooled it
- Brain Neuroplasticity Related to Lateral Ankle Ligamentous Injuries: A Systematic Review.Sports medicine (Auckland, N.Z.) · 2023Pooled it
- Functional characteristics in supraspinal networks and sensorimotor function following individualized dose-controlled HD-tDCS during foot core exercise in chronic ankle instability.Journal of sport and health science · 2026Article
- Article
- Biomechanical Abnormalities in Both Sides of Individuals With Unilateral Chronic Ankle Instability During Unanticipated Jumps.Orthopaedic journal of sports medicine · 2025Article
- Gait variability and biomechanical distinctions in individuals with functional ankle instability: a case-control study based on three-dimensional motion analysis.European journal of medical research · 2025Article
- No additive effect of transcranial direct current stimulation on balance exercises for brain activity and clinical outcomes in patients with chronic ankle instability: a randomised controlled trial.BMJ open sport & exercise medicine · 2025Article
- Middle and Long Latency Cutaneous Reflexes During the Stance Phase of Gait in Individuals with and Without Chronic Ankle Instability.Brain sciences · 2024Article
- Patients with chronic ankle instability exhibit increased sensorimotor cortex activation and correlation with poorer lateral balance control ability during single-leg stance: a FNIRS study.Frontiers in human neuroscience · 2024Article
- Effects of dual-task paradigm on the injury potential during landing among individuals with chronic ankle instability.Frontiers in physiology · 2024Article
- Altered regional neural activity and functional connectivity in patients with non-communicating hydrocephalus: a resting-state functional magnetic resonance imaging study.Frontiers in neurology · 2024Article
- Effects of whole-body vibration on sensorimotor deficits and brain plasticity among people with chronic ankle instability: a study protocol for a single-blind randomized controlled trial.BMC sports science, medicine & rehabilitation · 2023Article
- The effects of laser acupuncture dosage at PC6 (Neiguan) on brain reactivity: a pilot resting-state fMRI study.Frontiers in neuroscience · 2023Article
- Regional brain atrophy in patients with chronic ankle instability: A voxel-based morphometry study.Frontiers in neuroscience · 2022Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIncreasing evidence has proved that chronic ankle instability (CAI) is highly related to the central nervous system (CNS). However, it is still unclear about the inherent cerebral activity among the CAI patients. PURPOSE: To investigate the differences of intrinsic functional cerebral activity between the CAI patients and healthy controls (HCs) and further explore its correlation with clinical measurement in CAI patients. MATERIALS AND
methodsA total of 25 CAI patients and 39 HCs were enrolled in this study. Resting-state functional magnetic resonance imaging (rs-fMRI) was used to detect spontaneous cerebral activity. The metrics of amplitude of low-frequency fluctuation (ALFF), fractional ALFF (fALFF), and regional homogeneity (ReHo) of the two groups were compared by two-sample
resultsCompared with HCs, CAI patients showed higher ALFF and ReHo values in the right postcentral gyrus, the right precentral gyrus, and the right middle frontal gyrus, while lower fALFF values in the orbital-frontal cortex (OFC,
conclusionThe CAI patients exhibited enhanced and more coherent regional inherent neuronal activity within the sensorimotor network while lower regional inherent activity in pain/emotion modulation related region. In addition, the information exchanges were stronger within the sensorimotor network while weaker between distant interhemispheric regions. Besides, the increased inherent activity in the right middle frontal gyrus was related to clinical severity. These findings may provide insights into the pathophysiological alteration in CNS among CAI patients.
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