Evidence map›Paper›PMID 35197749›Full record

ArticleSaudi journal of biological sciences2022

Viridiflorol induces anti-neoplastic effects on breast, lung, and brain cancer cells through apoptosis.

Maaged A Akiel, Ohoud Y Alshehri, Shokran A Aljihani, Amani Almuaysib, Ammar Bader, Ahmed I Al-Asmari, Hassan S Alamri, Bahauddeen M Alrfaei, Majed A Halwani

Open access · hybridAbstract read
In one paragraph

Article in Saudi journal of biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Plants (Basel, Switzerland) · 2023
    Review
  10. Chemical Profiling and Bioactivity Assessment ofMolecules (Basel, Switzerland) · 2023
    Article
  11. Review
  12. Chemical Composition and Biological Activity ofPlants (Basel, Switzerland) · 2023
    Article
  13. Anti-Metabolites · 2023
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Maaged A AkielDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud Bin Abdulaziz University for Health Sciences (KSAU-HS), King Abdullah International Medical Research Center (KAIMRC), Riyadh, Saudi Arabia.
Ohoud Y AlshehriNanomedicine Department, King Abdullah International Medical Research Center/ King Abdulaziz Medical City, Ministry of National Guard, Health Affairs, Riyadh, Saudi Arabia.
Shokran A AljihaniNanomedicine Department, King Abdullah International Medical Research Center/ King Abdulaziz Medical City, Ministry of National Guard, Health Affairs, Riyadh, Saudi Arabia.
Amani AlmuaysibStem Cells and Regenerative Medicine, King Abdullah International Medical Research Center/ King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Ammar BaderFaculty of Pharmacy, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
Ahmed I Al-AsmariKing Abdul-Aziz Hospital, Laboratory Department, Ministry of Health, Jeddah, Saudi Arabia.
Hassan S AlamriDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud Bin Abdulaziz University for Health Sciences (KSAU-HS), King Abdullah International Medical Research Center (KAIMRC), Riyadh, Saudi Arabia.
Bahauddeen M AlrfaeiStem Cells and Regenerative Medicine, King Abdullah International Medical Research Center/ King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.
Majed A HalwaniNanomedicine Department, King Abdullah International Medical Research Center/ King Abdulaziz Medical City, Ministry of National Guard, Health Affairs, Riyadh, Saudi Arabia.
King Saud bin Abdulaziz University for Health Sciences · SAKing Abdullah International Medical Research Center · SAKing Abdulaziz Medical City · SAMinistry of Health · SAUmm al-Qura University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All active natural molecules are not fully exploited as therapeutic agents, causing delays in the advancement of anticancer drug discovery. Viridiflorol is a natural volatile element that may work as anti-cancer compound. We tested the anticancer properties of viridiflorol at different concentrations ranging from 0.03 to 300 μM

Indexed as

AnticancerApoptosisNatural productViridiflorol, Cytotoxicity, Drug discovery

Identifiers

PMID35197749
PMCPMC8847963
OpenAlexW3205508651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.