ArticleJournal of family & community medicine
Infection, reinfection, and postvaccination incidence of SARS-CoV-2 and associated risks in healthcare workers in Tamil Nadu: A retrospective cohort study.
Article in Journal of family & community medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 3 syntheses or guidelines pooled it, 9 citations in OpenAlex.
- Risk Factors Contributing to Reinfection by SARS-CoV-2: A Systematic Review.Advances in respiratory medicine · 2023Pooled it
- Incidence and outcome of SARS-CoV-2 reinfection in the pre-Omicron era: A global systematic review and meta-analysis.Journal of global health · 2023Pooled it
- COVID-19 vaccines reduce the risk of SARS-CoV-2 reinfection and hospitalization: Meta-analysis.Frontiers in medicine · 2022Pooled it
- Epidemiological characteristics of first-time SARS-CoV-2 Omicron infection among hospital staff in Chengdu, China.Journal of health, population, and nutrition · 2024Article
- Hybrid Immunity and the Incidence of SARS-CoV-2 Reinfections during the Omicron Era in Frontline Healthcare Workers.Vaccines · 2024Article
- Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe study was conducted in response to the need to understand the incidence of SARS-CoV2 infection and its determinants in healthcare workers (HCWs) and describe the epidemiology and presentation of reinfection cases. Also, we intended to determine the incidence of post-vaccination infections among health care workers as well as the contributing factors. MATERIALS AND
methodsRetrospective cohort design was used to quantify the coronavirus disease (COVID-19) infection among HCWs. The study cohort was all healthcare personnel working during the month of June 2021 in a tertiary care medical college hospital. Individuals diagnosed with laboratory-confirmed positive real-time polymerase chain reaction tests for SARS-CoV-2 infection between March 20, 2020, and May 31, 2021, were included. Univariate and multivariate analysis with Cox regression model elicited potential risk factors for all infections in HCWs.
resultsA total of 2420 HCWs constituted the cohort, in which the majority were primary healthcare providers (67.1%) and others. The mean age of the cohort was 30.27 years ± 10.53 standard deviation. The cumulative incidence of infection, reinfection, and postvaccination infection was 144.6 cases, 11.4 individuals, and 66.5 per 1000 HCWs respectively. Chronic illness was significantly associated with all infections. However, males and primary-care providers had higher risk of infection, whereas among the postvaccinated participants, partial vaccination status was one of the determinants.
conclusionBased on the findings, we endorse stringent testing and encourage HCWs to mandatorily follow COVID-appropriate behavior even if they are completely vaccinated and after recovery from previous infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.