Evidence map›Paper›PMID 35197684›Full record

ArticleJournal of human reproductive sciences

Role of Hysterosalpingography in Diagnosing Tubal Blockage - A Prospective Diagnostic Study.

Nikita Antonisamy, Nallamilli Sujatha Reddy, Parimala Chinta, Batiston Decruse Waanbah, Richa Samadhiya, T K Aleyamma, Belavendra Antonisamy, Mohan S Kamath

Open access · diamondAbstract read
In one paragraph

Article in Journal of human reproductive sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nikita AntonisamyDepartment of Reproductive Medicine and Surgery, Christian Medical College, Vellore, Tamil Nadu, India.
Nallamilli Sujatha ReddyDepartment of Reproductive Medicine and Surgery, Christian Medical College, Vellore, Tamil Nadu, India.
Parimala ChintaDepartment of Reproductive Medicine and Surgery, Christian Medical College, Vellore, Tamil Nadu, India.
Batiston Decruse WaanbahManda Clinic, Shillong, Meghalaya, India.
Richa SamadhiyaDepartment of Reproductive Medicine, Bansal Hospital, Bhopal, Madhya Pradesh, India.
T K AleyammaDepartment of Reproductive Medicine and Surgery, Christian Medical College, Vellore, Tamil Nadu, India.
Belavendra AntonisamyDepartment of Biostatistics, Christian Medical College, Vellore, Tamil Nadu, India.
Mohan S KamathDepartment of Reproductive Medicine and Surgery, Christian Medical College, Vellore, Tamil Nadu, India.
Christian Medical College & Hospital · INBansal Institute Of Research Technology & Science · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWomen with abnormal hysterosalpingography (HSG) are anxious regarding the presence of tubal pathology. It is important to know the predictive value of HSG and the need for subsequent laparoscopy following an abnormal report. In the era of assisted reproductive technology, the role of invasive testing such as diagnostic laparoscopy is being increasingly questioned due to its invasiveness and associated risks. There is a need to explore the positive predictive value (PPV) of HSG in detecting bilateral tubal block in our population as PPV changes with the prevalence of disease.

aimThe aim of this study was to evaluate the diagnostic accuracy of HSG in identifying tubal blockage in subfertile women. SETTING AND

designThis was a prospective diagnostic study conducted in the department of reproductive medicine and surgery in a university-level hospital. MATERIALS AND

methodsThe study included 199 subfertile women who had undergone HSG earlier and were planned for laparoscopy from April 2017 to January 2021. Findings of HSG and laparoscopy were compared with HSG as index test and laparoscopy as reference test, and the outcomes analysed were PPV of HSG for a bilateral tubal block, bilateral hydrosalpinx, abnormal HSG (unilateral or bilateral tubal block) and agreement between HSG and diagnostic laparoscopy in detecting normal and abnormal findings. STATISTICAL ANALYSIS: Kappa statistics, Stuart-Maxwell tests of marginal homogeneity and prevalence-adjusted bias-adjusted kappa (PABAK) statistics were used.

resultsThe PPV for a bilateral block with HSG was 20.9% (95% CI: 13.7-29.7). The PPV of HSG for bilateral hydrosalpinx was 50.0% (95% CI: 6.8-93.2). PABAK was estimated to be 0.42 (95% CI: 0.30-0.55), suggestive of moderate agreement between the tests. Findings of laparoscopy in women with at least one patent tube in HSG showed that in 12.3% of cases, the management was likely to change due to the operative findings.

conclusionThe current study showed low PPV for bilateral tubal block diagnosed with HSG which translates into a need for further confirmation by laparoscopy. In one out of every eight women with at least one patent tube on HSG, performing laparoscopy changed the management.

Indexed as

Hydrosalpinxhysterosalpingographylaparoscopypositive predictive valuetubal block

Identifiers

PMID35197684
PMCPMC8812393
OpenAlexW4200442768

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.