Evidence map›Paper›PMID 35197680›Full record

ArticleJournal of human reproductive sciences

Clinical Presentations and Semen Characteristics of Men Attending the Secondary Referral Infertility Clinic at Mumbai, India.

Shagufta Afzal Khan, Vijay R Kulkarni, Rupin S Shah, Jyotsna S Gokral, Pervin K Meherji, Ashok D Vadigoppula, Anushree D Patil, Aishwarya V Bhurke, Pratibha P Kokate, Ram S Barai and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of human reproductive sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Shagufta Afzal KhanClinical Research Laboratory and Andrology Clinic, ICMR-National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India.
Vijay R KulkarniClinical Research Laboratory and Andrology Clinic, ICMR-National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India.
Rupin S ShahClinical Research Laboratory and Andrology Clinic, ICMR-National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India.
Jyotsna S GokralDepartment of Clinical Research , ICMR- National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India.
Pervin K MeherjiDepartment of Clinical Research , ICMR- National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India.
Ashok D VadigoppulaClinical Research Laboratory and Andrology Clinic, ICMR-National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India.
Anushree D PatilDepartment of Clinical Research , ICMR- National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India.
Aishwarya V BhurkeClinical Research Laboratory and Andrology Clinic, ICMR-National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India.
Pratibha P KokateDepartment of Clinical Research , ICMR- National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India.
Ram S BaraiBiomedical Informatics Centre, ICMR-National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India.
Suchitra R SurveDepartment of Clinical Research , ICMR- National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India.
Deepak N ModiDepartment of Molecular and Cell Biology, ICMR-National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India.
Smita D MahaleEmeritus Scientist, ICMR-National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India.
Rahul K GajbhiyeClinical Research Laboratory and Andrology Clinic, ICMR-National Institute for Research in Reproductive Health, Mumbai, Maharashtra, India.
National Institute for Research in Reproductive Health · IN

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundLimited information is available on the aetiology and semen profiles of male infertility in Indian population.

aimThe aim of this study is to study the clinical and semen characteristics of men attending the infertility clinic and also to understand the impact of World Health Organization (WHO) 2010 reference values on the diagnosis of male infertility. SETTING AND

designA retrospective study evaluating the medical case records (January 2005 to December 2015, [ MATERIALS AND

methodsThe aetiology was classified based on the andrology evaluation and other investigations. Semen profiles were compared during the years 2005-2010 and 2011-2015 using WHO 1999 and WHO 2010 criteria, respectively. STATISTICAL ANALYSIS: The Chi-square and Mann-Whitney

resultsThe aetiology of male infertility was determined in 62% of the men; while the cause remained undetermined in 38%. Varicocele (25%), urogenital infections (10%), sexual dysfunctions (8%) and vas aplasia (8%) were identified as major aetiologies in our cohort. Men with sexual dysfunctions and vas aplasia were significantly higher during the years 2011-2015 as compared to 2005-2010. Men having normozoospermia (10%) and azoospermia (3%) were increased, whereas those having oligoasthenozoospermia (17%) were reduced in 2011-2015 as compared to 2005-2010. According to WHO 1999 criteria , 12-15% of men showed abnormal semen profiles. The semen parameters of these men became normal on using WHO 2010 reference values.

conclusionsVaricocele is the most common aetiology in infertile men. Idiopathic infertility was seen in a higher proportion among the infertile men.

Indexed as

Aetiology of male infertilitysemenspermvaricoceleWorld Health Organization reference value

Identifiers

PMID35197680
PMCPMC8812386
OpenAlexW4200014837

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.