Evidence map›Paper›PMID 35197631›Full record

ArticleNature2022

Ancient DNA and deep population structure in sub-Saharan African foragers.

Mark Lipson, Elizabeth A Sawchuk, Jessica C Thompson, Jonas Oppenheimer, Christian A Tryon, Kathryn L Ranhorn, Kathryn M de Luna, Kendra A Sirak, Iñigo Olalde, Stanley H Ambrose and 34 more

Abstract readHistorical Article
In one paragraph

Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed.

  1. Ancient DNA and Human Physiology.Physiology (Bethesda, Md.) · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Pan-African model explainsbioRxiv : the preprint server for biology · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Global patterns of natural selection inferred using ancient DNA.bioRxiv : the preprint server for biology · 2026
    Article
  14. Review
  15. Article
  16. Global impact of micronutrients in modern human evolution.American journal of human genetics · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

44 authors.

Mark Lipson *Department of Genetics, Harvard Medical School, Boston, MA, USA. mlipson@genetics.med.harvard.edu.
Elizabeth A Sawchuk *Department of Anthropology, University of Alberta, Edmonton, Alberta, Canada. esawchuk@ualberta.ca.ORCID http://orcid.org/0000-0003-4398-2174
Jessica C ThompsonDepartment of Anthropology and Peabody Museum of Natural History, Yale University, New Haven, CT, USA. jessica.thompson@yale.edu.ORCID http://orcid.org/0000-0003-1627-4949
Jonas OppenheimerDepartment of Biomolecular Engineering, University of California, Santa Cruz, Santa Cruz, CA, USA.
Christian A TryonDepartment of Anthropology, University of Connecticut, Storrs, CT, USA.ORCID http://orcid.org/0000-0002-2354-3273
Kathryn L RanhornInstitute of Human Origins, School of Human Evolution and Social Change, Arizona State University, Tempe, AZ, USA.ORCID http://orcid.org/0000-0002-9048-5966
Kathryn M de LunaDepartment of History, Georgetown University, Washington, DC, USA.ORCID http://orcid.org/0000-0002-3496-2115
Kendra A SirakDepartment of Genetics, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0003-2347-3479
Iñigo OlaldeDepartment of Genetics, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-2660-6807
Stanley H AmbroseDepartment of Anthropology, University of Illinois Urbana-Champaign, Urbana, IL, USA.ORCID http://orcid.org/0000-0002-8785-0512
John W ArthurDepartment of Anthropology, University of South Florida,, St Petersburg, FL, USA.ORCID http://orcid.org/0000-0002-4968-5843
Kathryn J W ArthurDepartment of Anthropology, University of South Florida,, St Petersburg, FL, USA.
George AyodoSchool of Health Sciences, Jaramogi Oginga Odinga University of Science and Technology, Bondo, Kenya.
Alex BertacchiDepartment of Anthropology and Peabody Museum of Natural History, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-2269-2437
Jessica I Cerezo-RománDepartment of Anthropology, University of Oklahoma, Norman, OK, USA.ORCID http://orcid.org/0000-0002-7752-8079
Brendan J CulletonInstitutes of Energy and the Environment, Pennsylvania State University, University Park, PA, USA.
Matthew C CurtisAnthropology Program, California State University-Channel Islands, Camarillo, CA, USA.ORCID http://orcid.org/0000-0003-4692-3241
Jacob DavisIndependent researcher, New Haven, CT, USA.
Agness O GidnaNational Museums of Tanzania, Dar es Salaam, Tanzania.
Annalys HansonSol Solutions LLC, Scottsdale, AZ, USA.
Potiphar KalibaMalawi Department of Museums and Monuments, Lilongwe, Malawi.
Maggie KatongoDepartment of Anthropology, Rice University, Houston, TX, USA.ORCID http://orcid.org/0000-0002-5286-1350
Amandus KwekasonNational Museums of Tanzania, Dar es Salaam, Tanzania.
Myra F LairdDepartment of Integrative Anatomical Sciences, University of Southern California, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-8636-0407
Jason LewisDepartment of Anthropology, Stony Brook University, Stony Brook, NY, USA.ORCID http://orcid.org/0000-0001-8325-1128
Audax Z P MabullaDepartment of Archaeology and Heritage Studies, University of Dar es Salaam, Dar es Salaam, Tanzania.
Fredrick MapembaMalawi Department of Museums and Monuments, Lilongwe, Malawi.
Alan MorrisDepartment of Human Biology, University of Cape Town, Cape Town, South Africa.
George MudendaLivingstone Museum, Livingstone, Zambia.
Raphael MwafulirwaMzuzu University, Mzuzu, Malawi.
Daudi MwangombaUniversity of Malawi, Zomba, Malawi.
Emmanuel NdiemaDepartment of Earth Sciences, National Museums of Kenya, Nairobi, Kenya.
Christine OgolaDepartment of Earth Sciences, National Museums of Kenya, Nairobi, Kenya.
Flora SchiltInterdisciplinary Center for Archaeology and Evolution of Human Behaviour (ICArEHB), FCHS, Universidade do Algarve, Faro, Portugal.ORCID http://orcid.org/0000-0002-2144-3017
Pamela R WilloughbyDepartment of Anthropology, University of Alberta, Edmonton, Alberta, Canada.
David K WrightDepartment of Archaeology, Conservation and History, University of Oslo, Oslo, Norway.ORCID http://orcid.org/0000-0003-1704-0423
Andrew ZipkinSchool of Human Evolution and Social Change, Arizona State University, Tempe, AZ, USA.ORCID http://orcid.org/0000-0002-3813-8051
Ron PinhasiDepartment of Evolutionary Anthropology, University of Vienna, Vienna, Austria.ORCID http://orcid.org/0000-0003-1629-8131
Douglas J KennettDepartment of Anthropology, University of California, Santa Barbara, CA, USA.ORCID http://orcid.org/0000-0001-6144-7365
Fredrick Kyalo ManthiDepartment of Earth Sciences, National Museums of Kenya, Nairobi, Kenya.
Nadin RohlandDepartment of Genetics, Harvard Medical School, Boston, MA, USA.
Nick PattersonDepartment of Human Evolutionary Biology, Harvard University, Cambridge, MA, USA.
David ReichDepartment of Genetics, Harvard Medical School, Boston, MA, USA. reich@genetics.med.harvard.edu.ORCID http://orcid.org/0000-0002-7037-5292
Mary E PrendergastDepartment of Genetics, Harvard Medical School, Boston, MA, USA. mary@rice.edu.ORCID http://orcid.org/0000-0003-0275-6795

Funding

Solving ascertainment bias in ancient DNA using Ultima Genomics sequencingR01HG012287 · NHGRI · HARVARD MEDICAL SCHOOL · PI REICH, DAVID E · 2021 to 2025
$2.7M
Population mixture in evolutionary and medical geneticsR01GM100233 · NIGMS · HARVARD MEDICAL SCHOOL · PI PATTERSON, NICK J, REICH, DAVID E · 2012 to 2019
$2.7M
Howard Hughes Medical InstituteNHGRI NIH HHS R01 HG012287NIGMS NIH HHS R01 GM100233
6 · The paper itself

Abstract

Multiple lines of genetic and archaeological evidence suggest that there were major demographic changes in the terminal Late Pleistocene epoch and early Holocene epoch of sub-Saharan Africa

Indexed as

Black PeopleDNA, AncientGenetics, PopulationAfrica South of the SaharaArchaeologyGene FlowGenome, HumanHistory, AncientHumansDNA, Ancient

Identifiers

PMID35197631
PMCPMC8907066

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.