Evidence map›Paper›PMID 35197627›Full record

ArticleNature2022

A global timing mechanism regulates cell-type-specific wiring programmes.

Saumya Jain, Ying Lin, Yerbol Z Kurmangaliyev, Javier Valdes-Aleman, Samuel A LoCascio, Parmis Mirshahidi, Brianna Parrington, S Lawrence Zipursky

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 54 citations in OpenAlex.

  1. Regulatory logic of neuronal differentiation in theProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Organization and evolution of sex-biased gene expression inbioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Regulatory logic of neuronal identity specification inbioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Nervous system-wide analysis of allScience advances · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Saumya Jain *Department of Biological Chemistry, University of California, Los Angeles, CA, USA.
Ying Lin *Department of Biological Chemistry, University of California, Los Angeles, CA, USA.
Yerbol Z KurmangaliyevHoward Hughes Medical Institute, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Javier Valdes-AlemanDepartment of Biological Chemistry, University of California, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-1577-1057
Samuel A LoCascioDepartment of Biological Chemistry, University of California, Los Angeles, CA, USA.
Parmis MirshahidiDepartment of Biological Chemistry, University of California, Los Angeles, CA, USA.
Brianna ParringtonDepartment of Biological Chemistry, University of California, Los Angeles, CA, USA.
S Lawrence ZipurskyDepartment of Biological Chemistry, University of California, Los Angeles, CA, USA. lzipursky@mednet.ucla.edu.ORCID http://orcid.org/0000-0001-5630-7181
Howard Hughes Medical Institute · USUniversity of California, Los Angeles · US

Funding

Training Grant in Neurobehavioral GeneticsT32NS048004 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BEARDEN, CARRIE E, OPHOFF, ROEL A · 2004 to 2025
$5.8M
Howard Hughes Medical InstituteNINDS NIH HHS T32 NS048004
6 · The paper itself

Abstract

The assembly of neural circuits is dependent on precise spatiotemporal expression of cell recognition molecules

Indexed as

Drosophila ProteinsEcdysoneAnimalsDrosophila melanogasterGene Expression RegulationSynapsesTranscription FactorsDrosophila ProteinsEcdysoneTranscription Factors

Identifiers

PMID35197627
OpenAlexW4212960115

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.