Evidence map›Paper›PMID 35197443›Full record

ArticleNature communications2022

Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission.

Dinesh Aggarwal, Andrew J Page, Ulf Schaefer, George M Savva, Richard Myers, Erik Volz, Nicholas Ellaby, Steven Platt, Natalie Groves, Eileen Gallagher and 11 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Effectiveness of international border control measures during the COVID-19 pandemic: a narrative synthesis of published systematic reviews.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2023
    Review
  5. Review
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  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 20 institutions in 2 countries.

Dinesh AggarwalUniversity of Cambridge, Department of Medicine, Cambridge, UK. dinesh.aggarwal@nhs.net.ORCID 0000-0002-5938-8172
Andrew J Page *Quadram Institute Bioscience, Norwich Research Park, Norwich, NR4 7UQ, UK.ORCID 0000-0001-6919-6062
Ulf Schaefer *Public Health England, 61 Colindale Ave, London, NW9 5EQ, UK.
George M SavvaQuadram Institute Bioscience, Norwich Research Park, Norwich, NR4 7UQ, UK.
Richard MyersPublic Health England, 61 Colindale Ave, London, NW9 5EQ, UK.
Erik VolzImperial College London, Department of Infectious Disease Epidemiology, London, UK.ORCID 0000-0001-6268-8937
Nicholas EllabyPublic Health England, 61 Colindale Ave, London, NW9 5EQ, UK.
Steven PlattPublic Health England, 61 Colindale Ave, London, NW9 5EQ, UK.
Natalie GrovesPublic Health England, 61 Colindale Ave, London, NW9 5EQ, UK.
Eileen GallagherPublic Health England, 61 Colindale Ave, London, NW9 5EQ, UK.
Niamh M TumeltyUniversity of Cambridge, Cambridge University Libraries, Cambridge, UK.ORCID 0000-0002-9894-6034
Thanh Le VietQuadram Institute Bioscience, Norwich Research Park, Norwich, NR4 7UQ, UK.ORCID 0000-0002-2106-8130
Gareth J HughesPublic Health England National Infections Service, Field Service, Leeds, UK.ORCID 0000-0002-3781-0117
Cong ChenPublic Health England, 61 Colindale Ave, London, NW9 5EQ, UK.
Charlie TurnerPublic Health England, 61 Colindale Ave, London, NW9 5EQ, UK.
Sophie LoganPublic Health England, National Infections Service, Field Service, Nottingham, UK.
Abbie HarrisonPublic Health England, 61 Colindale Ave, London, NW9 5EQ, UK.ORCID 0000-0002-7435-9994
COVID-19 Genomics UK (COG-UK) Consortium
Sharon J PeacockUniversity of Cambridge, Department of Medicine, Cambridge, UK.ORCID 0000-0002-1718-2782
Meera ChandPublic Health England, 61 Colindale Ave, London, NW9 5EQ, UK.
Ewan M HarrisonUniversity of Cambridge, Department of Medicine, Cambridge, UK. eh6@sanger.ac.uk.
Wellcome Sanger Institute · GBPublic Health England · GBUniversity of Cambridge · GBPublic Health Wales · GBMRC University of Glasgow Centre for Virus Research · GBUniversity of Birmingham · GBUniversity of Liverpool · GBUniversity of Sheffield · GBUniversity of Oxford · GBNorwich Research Park · GBCardiff University · GBUniversity of Nottingham · GBImperial College London · GBUniversity of Exeter · GBUniversity of Warwick · GBGuy's and St Thomas' NHS Foundation Trust · GBUniversity of Portsmouth · GBQueen's Medical Centre · GBUniversity College London · GBUniversity of Edinburgh · GB

Funding

Medical Research Council MC_PC_19012Medical Research Council MC_PC_19026Medical Research Council MC_PC_19027Medical Research Council MR/N029399/1Medical Research Council MR/R015600/1Medical Research Council MR/S00291X/1Wellcome Trust 204911/Z/16/ZWellcome Trust (Wellcome) 222903/Z/21/Z
6 · The paper itself

Abstract

Mitigation of SARS-CoV-2 transmission from international travel is a priority. We evaluated the effectiveness of travellers being required to quarantine for 14-days on return to England in Summer 2020. We identified 4,207 travel-related SARS-CoV-2 cases and their contacts, and identified 827 associated SARS-CoV-2 genomes. Overall, quarantine was associated with a lower rate of contacts, and the impact of quarantine was greatest in the 16-20 age-group. 186 SARS-CoV-2 genomes were sufficiently unique to identify travel-related clusters. Fewer genomically-linked cases were observed for index cases who returned from countries with quarantine requirement compared to countries with no quarantine requirement. This difference was explained by fewer importation events per identified genome for these cases, as opposed to fewer onward contacts per case. Overall, our study demonstrates that a 14-day quarantine period reduces, but does not completely eliminate, the onward transmission of imported cases, mainly by dissuading travel to countries with a quarantine requirement.

Indexed as

Communicable Diseases, ImportedContact TracingCOVID-19EnglandGenome, ViralGenomicsHealth Impact AssessmentHumansQuarantineSARS-CoV-2TravelTravel-Related Illness

Identifiers

PMID35197443
PMCPMC8866425
OpenAlexW4214655580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.