ArticleInternational journal of gynecological cancer : official journal of the International Gynecological Cancer Society2022
Disparity of ovarian cancer survival between urban and rural settings.
Article in International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Age-specific disparities in rural and urban survival among patients with IDH-wildtype glioblastoma: a population-based study.Cancer causes & control : CCC · 2026Article
- A mixed-methods approach for understanding cancer center catchment area needs: An example of rural cancer disparities, needs, and resiliencies.Cancer causes & control : CCC · 2026Article
- Ovarian Cancer Mortality Predictors in Public Oncology Centers, Addis Ababa, Ethiopia: A Case-Control Study.Cancer reports (Hoboken, N.J.) · 2026Article
- Urban-rural residence location and cancer-specific mortality among colorectal, lung and ovarian cancer patients: a nationwide retrospective cohort study from Lithuania.Acta oncologica (Stockholm, Sweden) · 2025Article
- Midwest Urban-Rural Differences in Cancer Prevalence.Mayo Clinic proceedings · 2025Article
- Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer.Annals of surgical oncology · 2023Review
- The mortalities of female-specific cancers in China and other countries with distinct socioeconomic statuses: A longitudinal study.Journal of advanced research · 2023Article
- Association of Distance to Gynecologic Oncologist and Survival in a Rural Midwestern State.Women's health reports (New Rochelle, N.Y.) · 2022Article
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8 authors.
Funding
Abstract
objectiveTo determine if there is a difference in overall survival of patients with epithelial ovarian cancer in rural, urban, and metropolitan settings in the United States.
methodsWe performed a retrospective cohort study using 2004-2016 National Cancer Database (NCDB) data including high and low grade, stage I-IV disease. Bivariate analyses used Student's t-test for continuous variables and χ
resultsA total of 111 627 patients were included with a mean age of 62.5 years for metroolitan (range 18-90), 64.0 years for rural (range 19-90) and 63.2 years for urban areas (range 18-90). Of all patients included, 94 290 were in a metropolitan area (counties >1 million population or 50 000-999 999), 15 386 were in an urban area (population of 10 000-49 999), and 1951 were in a rural area (non-metropolitan/non-core population). Univariate Cox proportional hazards models showed clinically significant differences in survival in patients from metropolitan, urban, and rural areas. Multivariate Cox proportional hazards models showed a clinically significant increase in HRs for patients in rural settings (HR 1.17; 95% CI 1.06 to 1.29). Increasing age and stage, non-insured status, non-white race, and comorbidity were also significant for poorer survival.
conclusionPatients with ovarian cancer who live in rural settings with small populations and greater distance to tertiary care centers have poorer survival. These differences hold after controlling for stage, age, and other significant risk factors related to poorer outcomes. To improve clinical outcomes, we need further studies to identify which of these factors are actionable.
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