Evidence map›Paper›PMID 35197277›Full record

ArticleEuropean journal of hospital pharmacy : science and practice2023

The potential for deprescribing in a palliative oncology patient population: a cross-sectional study.

Lisanne N van Merendonk, Bas J M Peters, Julia E Möhlmann, Cornelis B Hunting, Elisabeth A Kastelijn, Marcel P H van den Broek

Open access · greenAbstract read
In one paragraph

Article in European journal of hospital pharmacy : science and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lisanne N van MerendonkClinical Pharmacy, Sint Antonius Hospital, Nieuwegein, The Netherlands l.v.merendonk@nki.nl.ORCID 0000-0002-1166-529X
Bas J M PetersClinical Pharmacy, Sint Antonius Hospital, Nieuwegein, The Netherlands.
Julia E MöhlmannClinical Pharmacy, Sint Antonius Hospital, Nieuwegein, The Netherlands.
Cornelis B HuntingDepartment of Internal Medicine, Sint Antonius Hospital, Nieuwegein, The Netherlands.
Elisabeth A KastelijnDepartment of Pulmonary Diseases, Sint Antonius Hospital, Nieuwegein, The Netherlands.
Marcel P H van den BroekClinical Pharmacy, Sint Antonius Hospital, Nieuwegein, The Netherlands.
St. Antonius Ziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe use of preventive medication in palliative oncology patients may be inappropriate due to limited life expectancy. Deprescribing tools are available but time-consuming and not always tailored to this specific population. Our primary goal was to identify potentially inappropriate medications (PIMs) in palliative oncology patients with a life expectancy of up to 2 years using an adapted deprescribing tool. Our secondary aim was to identify patient characteristics associated with the presence of PIMs.

methodsOncology patients with a life expectancy of up to 2 years were included cross-sectionally. An adapted deprescribing tool was developed to identify PIMs. Logistic regression was used to identify factors associated with having PIMs.

resultsA total of 218 patients were included in this study of which 56% had at least one PIM with a population mean of 1.1 PIM per patient. Most frequently defined PIMs were antihypertensive drugs and gastric acid inhibitors. Identification of PIMs by review took an estimated 5-10 min per patient. Polypharmacy, age >65 years and inpatient/outpatient status were found to be associated with having at least one PIM.

conclusionsDeprescribing is possible in more than half of palliative oncology patients with a life expectancy of up to 2 years. The adapted deprescribing tool used is non-time consuming and suitable for palliative oncology patients, regardless of age.

Indexed as

DeprescriptionsNeoplasmsAgedCross-Sectional StudiesHumansInappropriate PrescribingPotentially Inappropriate Medication Listdrug misusemedical oncologypalliative carepharmacy service, hospitalpreventive medicine

Identifiers

PMID35197277
PMCPMC10800274
OpenAlexW4213430211

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.