Evidence map›Paper›PMID 35197107›Full record

ArticleEuropean journal of medical research2022

Low-dose radiation treatment for painful plantar enthesophyte: a highly effective therapy with little side effects.

Freddy Djiepmo, Bálint Tamaskovics, Edwin Bölke, Matthias Peiper, Jan Haussmann, Judith Neuwahl, Danny Jazmati, Kitti Maas, Livia Schmidt, Roman Gelzhäuser and 8 more

Open access · goldAbstract read
In one paragraph

Article in European journal of medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 2 countries.

Freddy Djiepmo *Department of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany.
Bálint Tamaskovics *Department of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany.ORCID http://orcid.org/0000-0002-2533-0167
Edwin BölkeDepartment of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany. boelke@med.uni-duesseldorf.de.ORCID http://orcid.org/0000-0001-9112-1024
Matthias PeiperMedical Faculty, Heinrich-Heine-University, Dusseldorf, Germany.
Jan HaussmannDepartment of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany.
Judith NeuwahlDepartment of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany.
Danny JazmatiDepartment of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany.
Kitti MaasDepartment of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany.
Livia SchmidtDepartment of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany.
Roman GelzhäuserInstitute of Mathematical Statistics and Probability Theory, Heinrich-Heine-University, Dusseldorf, Germany.
Christoph SchleichRadiology Dusseldorf/Viersen, Ernst-Schneider-Platz 1, Dusseldorf, Germany.
Stefanie CorradiniDepartment of Radiation Oncology, University Hospital, LMU Munich, Munich, Germany.
Klaus OrthUniversity of Hannover, Hannover, Germany.
Martijn van GriensvenDepartment cBITE, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, Maastricht, The Netherlands.
Amir RezazadehDepartment of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany.
Kimia KarimiDepartment of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany.
Wilfried BudachDepartment of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany.
Christiane MatuschekDepartment of Radiation Oncology, Heinrich Heine University, Dusseldorf, Germany.
Heinrich Heine University Düsseldorf · DELMU Klinikum · DEMaastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimPlantar enthesophyte is a common degenerative disorder. Surgical and medical treatment options are associated with either poor outcome or high percentage of relapse. Observations have indicated a beneficial effect of radiation therapy. We therefore wanted to evaluate pain reduction using orthovolt or cobalt-based radiation treatment for painful plantar enthesophyte and determine long-term response as well as prognostic parameters in this condition.

methodsWe identified a total of 102 consecutive patients treated for a total of 117 symptomatic heel spurs. 59 patients were treated with cobalt radiation, 31 patients with orthovolt therapy and 12 patients with both radiation systems. Primary outcome measure was pain reduction being scored using the modified Rowe Score prior therapy, at the end of each treatment series as well as after 6 weeks. Secondary outcome measure was long-term outcome, evaluated in patients with a follow-up period of longer than 3 years.

resultsBefore radiation therapy, 61 patients (60.4%) had a score of 0, significant strong pain. At the time of completion of radiation treatment, 3 patients (2.7%) were pain-free (score of 30), whereas 8 patients (7.9%) had still severe pain (score 0). 6 weeks after radiation therapy, 33 patients (32.7%) were pain-free and 8 patients (7.9%) had severe pain (score 0), while at the time data of collection, 74 patients (73%) were free of pain and 1 patient (1%) had strong pain (score 0). Duration of pain before the start of radiation treatment was a significant prognostic factor (p = 0.012) for response to treatment.

conclusionRadiotherapy of painful plantar enthesophyte is a highly effective therapy with little side effects providing long-term therapeutic response. The only significant prognostic parameter for response to treatment is the duration of pre-radiation therapy pain. Early integration of radiation therapy in the treatment seems to result in superior pain reduction.

Indexed as

AdultAgedAged, 80 and overFemaleFollow-Up StudiesHeel SpurHumansMaleMiddle AgedPainPain MeasurementPrognosisRadiographyRadiotherapy DosageTime FactorsTreatment OutcomeBenign diseaseElectronsHeel spurPainPhoton therapyPlantar enthesophyteRadiation therapy

Identifiers

PMID35197107
PMCPMC8867737
OpenAlexW4213233682

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.