Evidence map›Paper›PMID 35197101›Full record

ArticleJournal of orthopaedic surgery and research2022

Cervical non-fusion using biomimetic artificial disc and vertebra complex: technical innovation and biomechanics analysis.

Jialiang Li, Pengrong OuYang, Xijing He, Xinyu Wei, Zhongwei Sun, Hui Dong, Zhijing Wen, Yibin Wang, Pengzhen Gu, Teng Lu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Jialiang LiDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.
Pengrong OuYangDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.
Xijing HeDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China. xijing_h@vip.tom.com.ORCID http://orcid.org/0000-0002-0465-5376
Xinyu WeiDepartment of Health Management, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.
Zhongwei SunDepartment of Engineering Mechanics, School of Civil Engineering, Southeast University, Nanjing, China.
Hui DongDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.
Zhijing WenDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.
Yibin WangDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.
Pengzhen GuDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.
Teng LuDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.
Ning LiuDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.
Haopeng LiDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.
Second Affiliated Hospital of Xi'an Jiaotong University · CNSoutheast University · CN

Funding

shaanxi key science and technology innovation team project 2017ZDCXL-SF-01-05
6 · The paper itself

Abstract

backgroundChanges in spinal mobility after vertebral fusion are important factors contributing to adjacent vertebral disease (ASD). As an implant for spinal non-fusion, the motion-preserving prosthesis is an effective method to reduce the incidence of ASD, but its deficiencies hamper the application in clinical. This study designs a novel motion-preserving artificial cervical disc and vertebra complex with an anti-dislocation mechanism (MACDVC-AM) and verifies its effect on the cervical spine.

methodsThe MACDVC-AM was designed on the data of healthy volunteers. The finite element intact model, fusion model, and MACDVC-AM model were constructed, and the range of motion (ROM) and stress of adjacent discs were compared. The biomechanical tests were performed on fifteen cervical specimens, and the stability index ROM (SI-ROM) were calculated.

resultsCompared with the intervertebral ROMs of the intact model, the MACDVC-AM model reduced by 28-70% in adjacent segments and increased by 26-54% in operated segments, but the fusion model showed the opposite result. In contrast to the fusion model, the MACDVC-AM model diminished the stress of adjacent intervertebral discs. In biomechanical tests, the MACDVC-AM group showed no significant difference with the ROMs of the intact group (p > 0.05). The SI-ROM of the MACDVC-AM group is negative but close to zero and showed no significant difference with the intact group (p > 0.05).

conclusionsThe MACDVC-AM was successfully designed. The results indicate that the MACDVC-AM can provide physiological mobility and stability, reduce adjacent intervertebral compensatory motion, and alleviate the stress change of adjacent discs, which contributes to protect adjacent discs and reduce the occurrence of ASD.

Indexed as

BiomimeticsAdultBiomechanical PhenomenaCervical VertebraeFemaleFinite Element AnalysisHumansIntervertebral DiscMaleMiddle AgedRange of Motion, ArticularSpinal DiseasesSpinal FusionAdjacent segment diseaseBiomechanicsCervical vertebraeFinite element analysisProstheses and implantsRange of motion

Identifiers

PMID35197101
PMCPMC8867629
OpenAlexW4213043048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.