Evidence map›Paper›PMID 35197013›Full record

ArticleBMC infectious diseases2022

Epidemiological and clinical risk factors related to severe COVID-19 in Iran: a multi-center study.

Seyed Mohammad Hashemi-Shahri, Seyed Mohammad Nasiraldin Tabatabaei, Alireza Ansari-Moghaddam, Mahdi Mohammadi, Hassan Okati-Aliabad, Seyed Mehdi Tabatabaei, Hossein Ansari, Mohammadhadi Abbasi, Khodadad Sheikhzadeh, Mehdi Zanganeh Baygi and 7 more

Abstract readMulticenter Study
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Seyed Mohammad Hashemi-ShahriResearch Center for Infectious Diseases and Tropical Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
Seyed Mohammad Nasiraldin TabatabaeiDepartment of Anesthesiology, Zahedan University of Medical Sciences, Zahedan, Iran.
Alireza Ansari-MoghaddamHealth Promotion Research Center, Zahedan University of Medical Sciences Campus, Hesabi Square, Zahedan, Iran.
Mahdi MohammadiHealth Promotion Research Center, Zahedan University of Medical Sciences Campus, Hesabi Square, Zahedan, Iran.
Hassan Okati-AliabadHealth Promotion Research Center, Zahedan University of Medical Sciences Campus, Hesabi Square, Zahedan, Iran. dr.okati@zaums.ac.ir.ORCID http://orcid.org/0000-0002-9474-9842
Seyed Mehdi TabatabaeiResearch Center for Infectious Diseases and Tropical Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
Hossein AnsariHealth Promotion Research Center, Zahedan University of Medical Sciences Campus, Hesabi Square, Zahedan, Iran.
Mohammadhadi AbbasiHealth Promotion Research Center, Zahedan University of Medical Sciences Campus, Hesabi Square, Zahedan, Iran.
Khodadad SheikhzadehHealth Promotion Research Center, Zahedan University of Medical Sciences Campus, Hesabi Square, Zahedan, Iran.
Mehdi Zanganeh BaygiHealth Promotion Research Center, Zahedan University of Medical Sciences Campus, Hesabi Square, Zahedan, Iran.
Majid SartipiDepartment of Epidemiology and Biostatistics, School of Health, Zahedan University of Medical Sciences, Zahedan, Iran.
Sharareh Sanei-SistaniDepartment of Radiology, Zahedan University of Medical Sciences, Zahedan, Iran.
Ali Reza Salimi KhorashadResearch Center for Infectious Diseases and Tropical Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
Fatemeh Ansari-MoghadamHealth Promotion Research Center, Zahedan University of Medical Sciences Campus, Hesabi Square, Zahedan, Iran.
Neda TorabHealth Promotion Research Center, Zahedan University of Medical Sciences Campus, Hesabi Square, Zahedan, Iran.
Tahereh KhaliliDepartment of Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
Ghasem Miri-AliabadChildren and Adolescent Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIran was one of the first countries to be affected by COVID-19. Identifying factors associated with the severity of COVID-19 is effective in disease management. This study investigated the epidemiological and clinical features and factors related to the severity of COVID-19 in one of the less privileged areas in Iran.

methodsIn a multi-center study, all patients admitted to Zahedan University of Medical Sciences hospitals in southeastern Iran were investigated from February 29 to April 31, 2020. Demographic, epidemiological, and clinical data of patients were extracted from medical records. Bivariate and multivariate logistic regression models were used to explore the risk factors associated with the severity of COVID-19.

resultsAmong the 413 patients, 55.5% were male, and 145 (35.10%) were in a severe condition at admission time. Multivariate analysis showed that the adjusted odds of the disease severity increased in patients with older age (OR 2.27; 95% CI 1.41-3.65), substance abuse (OR 2.49; 95% CI 1.14-5.43), having one underlying disease (OR 1.52; 95% CI 0.90-2.55), having two underlying disease (OR 2.31; 95% CI 1.19-4.50), and having three or more underlying disease (OR 2.60; 95% CI 1.19-5.66).

conclusionsCOVID-19 was more severe in older patients, patients with a history of substance abuse, and patients with the underlying disease. Understanding the factors affecting the disease severity can help the clinical management of COVID-19, especially in less privileged areas where fewer resources are available.

Indexed as

COVID-19AgedHospitalizationHumansIranMaleRetrospective StudiesRisk FactorsSARS-CoV-2COVID-19PatientsRisk factorsSeverity

Identifiers

PMID35197013
PMCPMC8864589

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.