ArticleUltrasonography (Seoul, Korea)2022
A comparison of the diagnostic performance of the O-RADS, RMI4, IOTA LR2, and IOTA SR systems by senior and junior doctors.
Article in Ultrasonography (Seoul, Korea), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 4 of them syntheses that pooled it.
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Who cites it
31 citing papers in PubMed, 4 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Have Iota Simple Rules the Same Diagnostic Performance When Used by Nonexpert Examiners as Compared to Expert Examiners? Systematic Review and Meta-Analisis.Journal of clinical ultrasound : JCU · 2026Pooled it
- Comparison of the Diagnostic Performance of Ovarian Adnexal Reporting Data System (O-RADS) With IOTA Simple Rules and ADNEX Model for Classifying Adnexal Masses: A Head-To-Head Meta-Analysis.Journal of clinical ultrasound : JCU · 2025Pooled it
- Inter-reader reliability of Ovarian-Adnexal Reporting and Data System US: a systematic review and meta-analysis.Abdominal radiology (New York) · 2025Pooled it
- Comparison of O-RADS with the ADNEX model and IOTA SR for risk stratification of adnexal lesions: a systematic review and meta-analysis.Frontiers in oncology · 2024Pooled it
- Performance of International Ovarian Tumor Analysis Simple Rules and Ovarian-Adnexal Reporting and Data System for classifying benign and malignant pediatric adnexal lesions using ultrasound.Pediatric radiology · 2026Article
- AI-Assisted Papillary Thyroid Carcinoma Localization on Cervical Non-contrast CT: A Multicenter Validation and Two-Reader Pilot Study of a Standalone Executable nnU-Net Software.Journal of imaging informatics in medicine · 2026Article
- Construction of a nomogram model for predicting benignity and malignancy in adnexal masses.Ultrasonography (Seoul, Korea) · 2026Article
- Analysis of the efficacy of adnexal mass diagnosis by senior and junior sonologists based on subjective diagnosis and O-RADS classification.BMC women's health · 2026Article
- Assessment of ultrasound ovarian-adnexal reporting & data system (O-RADS) for pediatric patients.Pediatric radiology · 2026Article
- Development and Validation of Differential Diagnosis Models and Nomograms Based on Serum D-Dimer and Other Multimodal Information for Borderline and Benign Epithelial Ovarian Tumors: A Multicenter Study.Diagnostics (Basel, Switzerland) · 2025Article
- O-RADS US versus IOTA simple rules in the diagnosis of benign and malignant adnexal masses: a prospective study.BMC medical imaging · 2025Article
- Accurate prediction of benign and malignant adnexal tumors in surgical resection and conservative treatment: construction and external validation of a diagnostic model based on CEUS, HE4, and O-RADS US v2022 evaluation.Journal of ovarian research · 2025Article
- Diagnostic performances of the Ovarian Adnexal Reporting and Data System, the Risk of Ovarian Malignancy Algorithm, and the Copenhagen Index in the preoperative prediction of ovarian cancer: a prospective cohort study.Journal of gynecologic oncology · 2025Article
- Automatic segmentation model and machine learning model grounded in ultrasound radiomics for distinguishing between low malignant risk and intermediate-high malignant risk of adnexal masses.Insights into imaging · 2025Article
- Advancements in artificial intelligence for ultrasound diagnosis of ovarian cancer: a comprehensive review.Frontiers in oncology · 2025Review
- Article
- Comparison of Simple Ultrasound Rules by International Ovarian Tumor Analysis (IOTA) with RMI-1 and RMI-4 (Risk of Malignancy Index) in Preoperative Differentiation of Benign and Malignant Adnexal Masses.Journal of obstetrics and gynaecology of India · 2024Article
- Clinical value of ACR O-RADS combined with CA125 in the risk stratification of adnexal masses.Frontiers in oncology · 2024Article
- Application of O-RADS US combined with MV-Flow to diagnose ovarian-adnexal tumors.Ultrasonography (Seoul, Korea) · 2024Article
- Ultrasound image-based nomogram combining clinical, radiomics, and deep transfer learning features for automatic classification of ovarian masses according to O-RADS.Frontiers in oncology · 2024Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study compared the diagnostic performance of the Ovarian-Adnexal Reporting and Data System (O-RADS), the Risk of Malignancy Index 4 (RMI4), the International Ovarian of Tumor Analysis Logistic Regression Model 2 (IOTA LR2), and the IOTA Simple Rules (IOTA SR) in predicting the malignancy of adnexal masses (AMs).
methodsThis retrospective study included 575 women with AMs between 2017 and 2020. All clinical messages, ultrasound images, and pathological findings were collected. Two senior doctors (group I) and two junior doctors (group II) used the four systems to classify AMs. The postoperative pathological diagnosis was used as the gold standard to evaluate the diagnostic efficiency. A receiver operating characteristic curve was used to test the diagnostic performance. The interrater agreement between the two groups was tested using kappa values.
resultsOf all 592 AMs, 447 (75.5%) were benign, 123 (20.8%) were malignant, and 22 (3.7%) were borderline. The intergroup consistency test yielded kappa values of 0.71, 0.92, 0.68, and 0.77 for the O-RADS, RMI4, IOTA LR2, and IOTA SR, respectively. To predict malignant lesions, the areas under the curve of the O-RADS, RMI4, IOTA LR2, and IOTA SR systems were 0.90, 0.89, 0.90, and 0.86 for group I and 0.89, 0.87, 0.88, and 0.84 for group II, respectively. The O-RADS had the highest sensitivity (91.0% in group I and 84.8% in group II).
conclusionThe four diagnostic systems could compensate for junior doctors' inexperience in predicting malignant adnexal lesions. The O-RADS performed best and showed the highest sensitivity.
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