Evidence map›Paper›PMID 35196819›Full record

ArticleMicrobiology spectrum2022

Estimating SARS-CoV-2 Seroprevalence in Canadian Blood Donors, April 2020 to March 2021: Improving Accuracy with Multiple Assays.

Ashleigh R Tuite, David Fisman, Kento T Abe, Bhavisha Rathod, Adrian Pasculescu, Karen Colwill, Anne-Claude Gingras, Qi-Long Yi, Sheila F O'Brien, Steven J Drews

Abstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ashleigh R TuiteDalla Lana School of Public Health, University of Torontogrid.17063.33, Toronto, Ontario, Canada.
David FismanDalla Lana School of Public Health, University of Torontogrid.17063.33, Toronto, Ontario, Canada.
Kento T AbeLunenfeld-Tanenbaum Research Institute at Mt. Sinai Hospital, Sinai Health, Toronto, Ontario, Canada.
Bhavisha RathodLunenfeld-Tanenbaum Research Institute at Mt. Sinai Hospital, Sinai Health, Toronto, Ontario, Canada.
Adrian PasculescuLunenfeld-Tanenbaum Research Institute at Mt. Sinai Hospital, Sinai Health, Toronto, Ontario, Canada.
Karen ColwillLunenfeld-Tanenbaum Research Institute at Mt. Sinai Hospital, Sinai Health, Toronto, Ontario, Canada.
Anne-Claude GingrasLunenfeld-Tanenbaum Research Institute at Mt. Sinai Hospital, Sinai Health, Toronto, Ontario, Canada.
Qi-Long YiEpidemiology and Surveillance, Canadian Blood Servicesgrid.423370.1, Ottawa, Ontario, Canada.
Sheila F O'BrienEpidemiology and Surveillance, Canadian Blood Servicesgrid.423370.1, Ottawa, Ontario, Canada.
Steven J DrewsCanadian Blood Servicesgrid.423370.1, Microbiology, Edmonton, Alberta, Canada.ORCID 0000-0003-2519-1109

Funding

Abbott | Abbott Diagnostics Partial kit costAlberta Innovates G2020000360DrewsGouvernement du Canada | Canadian Institutes of Health Research (IRSC) VR2-172723
6 · The paper itself

Abstract

We have previously used composite reference standards and latent class analysis (LCA) to evaluate the performance of laboratory assays in the presence of tarnished gold standards. Here, we apply these techniques to repeated, cross-sectional study of Canadian blood donors, whose sera underwent parallel testing with four separate SARS-CoV-2 antibody assays. We designed a repeated cross-sectional design with random cross-sectional sampling of all available retention samples (

Indexed as

AdultAgedAntibodies, ViralBlood DonorsCanadaCoronavirus Nucleocapsid ProteinsCOVID-19Cross-Sectional StudiesEnzyme-Linked Immunosorbent AssayFemaleHumansMaleMiddle AgedSARS-CoV-2Seroepidemiologic StudiesSpike Glycoprotein, CoronavirusAntibodies, ViralCoronavirus Nucleocapsid ProteinsSpike Glycoprotein, CoronavirusIgGlatent class analysisnucleocapsidreceptor binding domainSARS-CoV-2 antibodyspike

Identifiers

PMID35196819
PMCPMC8865569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.