Evidence map›Paper›PMID 35196132›Full record

ArticlemSystems2022

Reduced Virulence and Enhanced Host Adaption during Antibiotics Therapy: a Story of a Within-Host Carbapenem-Resistant Klebsiella pneumoniae Sequence Type 11 Evolution in a Patient with a Serious Scrotal Abscess.

Meiping Ye, Chunjie Liao, Mengya Shang, Danyang Zou, Xin Feng, Xinying Lu, Yixin Zhang, Jingmin Yan, Zhixiang Hu, Xiaogang Xu and 2 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in mSystems, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Hypervirulent Carbapenem-resistantInfection and drug resistance · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Co-occurrence of ST412mSystems · 2024
    Article
  9. Does Emerging Carbapenem Resistance inInfectious disease reports · 2023
    Review
  10. Frontiers in microbiology · 2023
    Review
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Meiping Ye *STD Institute, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China.
Chunjie Liao *Shanghai Skin Disease Hospital, Clinical School of Anhui Medical University, Shanghai, China.
Mengya Shang *Shanghai Skin Disease Hospital, Clinical School of Anhui Medical University, Shanghai, China.
Danyang ZouSTD Institute, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China.
Xin FengSTD Institute, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China.
Xinying LuSTD Institute, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China.
Yixin ZhangInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.
Jingmin YanShanghai Skin Disease Hospital, Clinical School of Anhui Medical University, Shanghai, China.
Zhixiang HuSTD Institute, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China.
Xiaogang XuInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.
Jianping JiangInstitute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.ORCID 0000-0002-1066-6362
Pingyu ZhouSTD Institute, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China.
Tongji University · CNAnhui Medical University · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbapenem-resistant Klebsiella pneumoniae (CRKP) has disseminated globally and threatened human life. The sequence type (ST) 11 CRKP is a dominant clone in Asia, but how this clone evolves

Indexed as

Klebsiella InfectionsLiver AbscessAnti-Bacterial AgentsCarbapenemsHost AdaptationHumansKlebsiella pneumoniaeTigecyclineVirulenceAnti-Bacterial AgentsCarbapenemsTigecyclinegenomic studyhost adaptationin vivo evolutionRNA-seqvirulence attenuation

Identifiers

PMID35196132
PMCPMC9040587
OpenAlexW4213418608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.