ArticlemSphere2022
Diversity of Pseudomonas aeruginosa Temperate Phages.
Article in mSphere, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 41 citations in OpenAlex.
- Comparative Genomic Analysis of Pseudomonas shahriarae Reveals Virulence Potential, Antimicrobial Resistance, and Environmental Adaptation.Current microbiology · 2026Article
- Synergistic Efficiency of a Novel Temperate Phage YF1204 and Amikacin Against Carbapenem-ResistantMicroorganisms · 2026Article
- Comparative genomics insights into Pseudomonas rhodesiae: environmental distribution, resistance determinants, virulence factors, and evolutionary implications.BMC genomics · 2026Article
- Effect of temperate phage SapYZUs891 as a biocontrol agent on the Chinese foodborne multidrug-resistant Staphylococcus aureus isolates.Archives of microbiology · 2026Article
- Steering the course: targeting and exploiting surface receptors in phage therapy.Journal of bacteriology · 2026Review
- Extensive hidden prophage diversity inMicrobiology (Reading, England) · 2026Article
- PDP-Miner: an AI/ML tool to detect prophage tail proteins with depolymerase domains across thousands of bacterial genomes.Bioinformatics (Oxford, England) · 2025Article
- Role of R5 pyocin in the predominance of high-risk Pseudomonas aeruginosa isolates.Microbiological research · 2025Article
- Dark Matter Carried byInternational journal of molecular sciences · 2025Article
- Article
- Genomic variation inMicrobiology spectrum · 2025Article
- Pseudomonas aeruginosa maintains an inducible array of novel and diverse prophages over lengthy persistence in cystic fibrosis lungs.FEMS microbiology letters · 2025Article
- Systematic bacteriophage selection for the lysis of multipleFrontiers in cellular and infection microbiology · 2025Article
- Hot Spots of Site-Specific Integration into theInternational journal of molecular sciences · 2024Article
- Simultaneous clonal spread of NDM-1-producingIJID regions · 2024Article
- Genetic determinants of antimicrobial resistance in polymyxin B resistant Pseudomonas aeruginosa isolated from airways of patients with cystic fibrosis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024Article
- The role of filamentous matrix molecules in shaping the architecture and emergent properties of bacterial biofilms.The Biochemical journal · 2024Review
- Tailless and filamentous prophages are predominant in marine Vibrio.The ISME journal · 2024Article
- Structural and Genomic Diversity of Bacteriophages.Methods in molecular biology (Clifton, N.J.) · 2024Review
- Gut phageome: challenges in research and impact on human microbiota.Frontiers in microbiology · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Modern sequencing technologies have provided insight into the genetic diversity of numerous species, including the human pathogen Pseudomonas aeruginosa. Bacterial genomes often harbor bacteriophage genomes (prophages), which can account for upwards of 20% of the genome. Prior studies have found P. aeruginosa prophages that contribute to their host's pathogenicity and fitness. These advantages come in many different forms, including the production of toxins, promotion of biofilm formation, and displacement of other P. aeruginosa strains. While several different genera and species of P. aeruginosa prophages have been studied, there has not been a comprehensive study of the overall diversity of P. aeruginosa-infecting prophages. Here, we present the results of just such an analysis. A total of 6,852 high-confidence prophages were identified from 5,383 P. aeruginosa genomes from strains isolated from the human body and other environments. In total, 3,201 unique prophage sequences were identified. While 53.1% of these prophage sequences displayed sequence similarity to publicly available phage genomes, novel and highly mosaic prophages were discovered. Among these prophages, there is extensive diversity, including diversity within the functionally conserved integrase and C repressor coding regions, two genes responsible for prophage entering and persisting through the lysogenic life cycle. Analysis of integrase, C repressor, and terminase coding regions revealed extensive reassortment among P. aeruginosa prophages. This catalog of P. aeruginosa prophages provides a resource for future studies into the evolution of the species.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.