Evidence map›Paper›PMID 35196094›Full record

ArticleScience advances2022

A circuit from dorsal hippocampal CA3 to parvafox nucleus mediates chronic social defeat stress-induced deficits in preference for social novelty.

Yang Liu, Si-Long Deng, Liang-Xia Li, Zi-Xiang Zhou, Qiu Lv, Zhong-Yuan Wang, Fang Wang, Jian-Guo Chen

Abstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  5. Divergent BLA engram circuits orchestrate social preference dynamics in bystander male mice with self-experienced stress.Proceedings of the National Academy of Sciences of the United States of America · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yang LiuDepartment of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.ORCID 0000-0002-5899-7478
Si-Long DengDepartment of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.ORCID 0000-0002-4324-4326
Liang-Xia LiDepartment of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.ORCID 0000-0003-3033-0759
Zi-Xiang ZhouDepartment of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Qiu LvDepartment of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.ORCID 0000-0002-8418-3339
Zhong-Yuan WangDepartment of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.ORCID 0000-0001-6948-9199
Fang WangDepartment of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.ORCID 0000-0002-4781-8673
Jian-Guo ChenDepartment of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.ORCID 0000-0002-7805-3589

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The preference for social novelty is crucial to the social life of humans and rodents. However, the neural mechanisms underlying social novelty preference are poorly understood. Here, we found that chronic social defeat stress (CSDS) reduced the preference for social novelty in mice by impairing the response of CaMKIIα

Indexed as

Social DefeatStress, PsychologicalAnimalsForkhead Transcription FactorsGABAergic NeuronsHippocampusMiceMice, Inbred C57BLSocial BehaviorForkhead Transcription FactorsFoxb1 protein, mouse

Identifiers

PMID35196094
PMCPMC8865774

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.