Evidence map›Paper›PMID 35195912›Full record

ReviewCancer2022

New directions in cancer and aging: State of the science and recommendations to improve the quality of evidence on the intersection of aging with cancer control.

Lindsay C Kobayashi, Ashly C Westrick, Aalap Doshi, Katrina R Ellis, Carly R Jones, Elizabeth LaPensee, Alison M Mondul, Megan A Mullins, Lauren P Wallner

Open access · hybridAbstract readReview
In one paragraph

Review in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Allostatic Load, Multimorbidity, and Overall and Cancer-Specific Survival among Older Adults in the United States.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  2. Functional limitations among adult cancer survivors in the United States.Journal of cancer survivorship : research and practice · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Does Neighborhood Socioeconomic Status Alter Memory Change Associated with a Cancer Diagnosis? Preliminary Evidence from the US Health and Retirement Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  7. The geriatric Asia-Pacific oncology nursing imperative.Asia-Pacific journal of oncology nursing · 2023
    Article
  8. Perspectives on Aging and Quality of Life.Healthcare (Basel, Switzerland) · 2023
    Review
  9. Validation of Self-Reported Cancer Diagnoses by Respondent Cognitive Status in the U.S. Health and Retirement Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Lindsay C KobayashiDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan.ORCID 0000-0003-2725-3107
Ashly C WestrickDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan.
Aalap DoshiMichigan Institute for Clinical and Health Research, University of Michigan, Ann Arbor, Michigan.
Katrina R EllisRogel Cancer Center, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0003-1709-3912
Carly R JonesUniversity of Michigan School of Social Work, Ann Arbor, Michigan.
Elizabeth LaPenseeMichigan Institute for Clinical and Health Research, University of Michigan, Ann Arbor, Michigan.
Alison M MondulDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan.ORCID 0000-0002-8843-1416
Megan A MullinsRogel Cancer Center, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0003-2753-9068
Lauren P WallnerDepartment of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan.ORCID 0000-0002-1279-8617
University of Michigan · US

Funding

XenograftP30CA046592 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Eric R. Fearon · 1988 to 2026
$178.2M
Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Statistical Data EnclaveP30AG012846 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VICKI A. FREEDMAN · 1999 to 2026
$23.2M
Michigan Center for Urban African American Aging Research - RESEARCH CORE (REC)P30AG015281 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PETER A. LICHTENBERG, ROBERT Joseph TAYLOR · 1997 to 2026
$19.3M
Interdisciplinary Research Training Center in Cancer Care DeliveryT32CA236621 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lauren P Wallner · 2020 to 2026
$2.8M
Education and cancer-related cognitive decline during agingR03CA241841 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KOBAYASHI, LINDSAY C · 2019 to 2020
$156k
NCATS NIH HHS UL1 TR002240NCI NIH HHS P30 CA046592NCI NIH HHS R03 CA241841NCI NIH HHS T32 CA236621NIA NIH HHS P30 AG012846NIA NIH HHS P30 AG015281
6 · The paper itself

Abstract

backgroundThe global population of older cancer survivors is growing. However, the intersections of aging-related health risks across the cancer control continuum are poorly understood, limiting the integration of aging into cancer control research and practice. The objective of this study was to review the state of science and provide future directions to improve the quality of evidence in 6 priority research areas in cancer and aging.

methodsThe authors identified priority research areas in cancer and aging through an evidence-based Research Jam process involving 32 investigators and trainees from multiple disciplines and research centers in aging and cancer; then, they conducted a narrative review of the state of the science and future directions to improve the quality of evidence in these research areas. Priority research areas were defined as those in which gaps in scientific evidence or clinical practice limit the health and well-being of older adults with cancer.

resultsSix priority research areas were identified: cognitive and physical functional outcomes of older cancer survivors, sampling issues in studies of older cancer survivors, risk and resilience across the lifespan, caregiver support and well-being, quality of care for older patients with cancer, and health disparities. Evidence in these areas could be improved through the incorporation of bias reduction techniques into longitudinal studies of older cancer survivors, novel data linkage, and improved representation of older adults in cancer research.

conclusionsThe priority research areas and methodologies identified here may be used to guide interdisciplinary research and improve the quality of evidence on cancer and aging.

Indexed as

NeoplasmsAgedAgingHumansagingcaregivingcognitive functionhealth disparitiesinterdisciplinary researchlife coursemethodologyphysical functionsampling

Identifiers

PMID35195912
PMCPMC9007869
OpenAlexW4212847959

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.