Evidence map›Paper›PMID 35195751›Full record

SynthesisEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2023

Postoperative mortality in the COVID-positive hip fracture patient, a systematic review and meta-analysis.

Alexander Isla, David Landy, Robert Teasdall, Peter Mittwede, Ashley Albano, Paul Tornetta, Mohit Bhandari, Arun Aneja

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Observational
  2. Article
  3. Delay to surgery beyond 12 hours is associated with increased hip fracture mortality.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Implications of COVID-19 on hip fracture care discharge locations during the early stages of the pandemic.OTA international : the open access journal of orthopaedic trauma · 2023
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexander IslaDepartment of Orthopaedic Surgery, University of Kentucky, 740 South Limestone, Suite K413, Lexington, KY, 40536-0284, USA.ORCID http://orcid.org/0000-0003-1318-4323
David LandyDepartment of Orthopaedic Surgery, University of Kentucky, 740 South Limestone, Suite K413, Lexington, KY, 40536-0284, USA.ORCID http://orcid.org/0000-0002-4024-7679
Robert TeasdallDepartment of Orthopaedic Surgery, University of Kentucky, 740 South Limestone, Suite K413, Lexington, KY, 40536-0284, USA.ORCID http://orcid.org/0000-0001-6858-344X
Peter MittwedeUniversity of Pittsburgh, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0002-1200-9067
Ashley AlbanoDepartment of Orthopaedic Surgery, University of Kentucky, 740 South Limestone, Suite K413, Lexington, KY, 40536-0284, USA.ORCID http://orcid.org/0000-0002-0050-1732
Paul TornettaBoston University Medical Center, Boston, MA, USA.ORCID http://orcid.org/0000-0001-9219-9683
Mohit BhandariMcMaster University, Hamilton, ON, Canada.ORCID http://orcid.org/0000-0003-3556-9179
Arun AnejaDepartment of Orthopaedic Surgery, University of Kentucky, 740 South Limestone, Suite K413, Lexington, KY, 40536-0284, USA. aan247@uky.edu.ORCID http://orcid.org/0000-0002-1507-6863

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe extent to which concomitant COVID-19 infection increases short-term mortality following hip fracture is not fully understood. A systemic review and meta-analysis of COVID-19 positive hip fracture patients (CPHFPs) undergoing surgery was conducted to explore the association of COVID-19 with short-term mortality.

methodsReview of the literature identified reports of short-term 30-day postoperative mortality in CPHFPs. For studies including a contemporary control group of COVID-19 negative patients, odds ratios of the association between COVID-19 infection and short-term mortality were calculated. Short-term mortality and the association between COVID-19 infection and short-term mortality were meta-analyzed and stratified by hospital screening type using random effects models.

resultsSeventeen reports were identified. The short-term mortality in CPHFPs was 34% (95% C.I., 30-39%). Short-term mortality differed slightly across studies that screened all patients, 30% (95% C.I., 22-39%), compared to studies that conditionally screened patients, 36% (95% C.I., 31-42%), (P = 0.22). The association between COVID-19 infection and short-term mortality produced an odds ratio of 7.16 (95% C.I., 4.99-10.27), and this was lower for studies that screened all patients, 4.08 (95% C.I., 2.31-7.22), compared to studies that conditionally screened patients, 8.32 (95% C.I., 5.68-12.18), (P = 0.04).

conclusionCPHFPs have a short-term mortality rate of 34%. The odds ratio of short-term mortality was significantly higher in studies that screened patients conditionally than in studies that screened all hip fracture patients. This suggests mortality prognostication should consider how COVID-19 infection was identified as asymptomatic patients may fare slightly better.

Indexed as

COVID-19Hip FracturesHospital MortalityHumansRetrospective StudiesCOVID-19Hip fractureMortalitySARS-CoV-2

Identifiers

PMID35195751
PMCPMC8864596

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.