Trial reportInternational urogynecology journal2022
The efficacy and safety of a single maintenance laser treatment for stress urinary incontinence: a double-blinded randomized controlled trial.
Trial report in International urogynecology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 6 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- The Use of Energy-Based Devices for the Treatment of Stress Urinary Incontinence: A Systematic Review and Meta Analysis of the Randomised Sham-Controlled Trials.International urogynecology journal · 2026Pooled it
- Vaginal lasers for treating stress urinary incontinence in women.The Cochrane database of systematic reviews · 2025Pooled it
- Exploring the role of laser therapy for stress urinary incontinence: a literature review.Lasers in medical science · 2025Pooled it
- Conservative treatments for women with stress urinary incontinence: a systematic review and network meta-analysis.Frontiers in medicine · 2024Pooled it
- Evaluation of Possible Side Effects in the Treatment of Urinary Incontinence with Magnetic Stimulation.Medicina (Kaunas, Lithuania) · 2023Pooled it
- Effect of vaginal energy-based treatment on female stress urinary incontinence: a systematic review and meta-analysis of randomized controlled trials.World journal of urology · 2023Pooled it
- Vaginal Erbium Laser for the Treatment of Mild-to-Moderate Stress Urinary Incontinence: A Multicentre Randomised Sham-Controlled Trial.BJOG : an international journal of obstetrics and gynaecology · 2026Trial
- Vaginal Erbium Laser Versus Pelvic Floor Muscle Training for Stress Urinary Incontinence: A Randomised Controlled Trial.International urogynecology journal · 2025Trial
- Fractional COInternational urogynecology journal · 2023Trial
- Non-ablative transurethral laser treatment for collagen remodeling with functional recovery in an in vivo model of stress urinary incontinence.Scientific reports · 2026Article
- Modern Conservative Management Strategies for Female Stress Urinary Incontinence: A Systematic Review.Journal of clinical medicine · 2025Review
- A new approach to treatment of stress urinary incontinence using non-ablative transurethral laser.Scientific reports · 2025Article
- Predictors of the efficacy of CO 2 laser therapy for female stress urinary incontinence.Journal of the Chinese Medical Association : JCMA · 2025Article
- Current Treatment of Stress Urinary Incontinence by Bulking Agents and Laser Therapy-An Update.Journal of clinical medicine · 2024Review
- Treating and Managing Urinary Incontinence: Evolving and Potential Multicomponent Medical and Lifestyle Interventions.Research and reports in urology · 2023Review
- Vaginal Laser Therapy for Stress Urinary Incontinence: A Systematic Review of Prospective Randomized Clinical Trials.Journal of menopausal medicine · 2022Review
- COTherapeutic advances in urologyReview
- Current approaches and innovations in the management of female stress urinary incontinence: presentations from the first International Functional and Reconstructive Urology Update conference.Therapeutic advances in urologyArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introduction and hypothesisTo evaluate the efficacy and safety of a single carbon dioxide (CO
methodsWomen aged 40-70 years who experienced temporary significant improvement in symptoms following CO
resultsOf 183 women screened, 131 were included in the final analysis. Demographic characteristics and baseline measures in the outcome tests were similar between the groups. Statistically significant improvements were demonstrated in the study compared to the control group at 3 months post-treatment in positive cough test (44.4% vs. 79.4%, P = 0.002), mean pad weight test (2.3 g ± 1.3 vs. 5.6 ± 1.1, P < 0.001), mean UDI-6(24.7 ± 12.1 vs. 45.1 ± 13.6 SD, P = 0.004), mean ICIQ-UI (16.5 ± 4.3 vs. 10.3 + 3.8, P = 0.003) and mean PISQ-12 (21.3 ± 6.8 vs. 36.6 ± 7.5, P = 0.003). However, values at 6 months post-treatment were similar to those at baseline.
conclusionsOur results suggest that a single maintenance laser treatment for reducing symptoms of SUI is transiently effective, well tolerated and safe. This treatment modality provides alternative non-surgical therapy for women with SUI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.