Evidence map›Paper›PMID 35195270›Full record

Observational studyActa orthopaedica2022

Fast-track revision hip arthroplasty: a multicenter cohort study on 1,345 elective aseptic major component revision hip arthroplasties.

Martin Lindberg-Larsen, Pelle Baggesgaard Petersen, Yasemin Corap, Kirill Gromov, Christoffer Calov Jørgensen, Henrik Kehlet, Centre for Fast-track Hip and Knee Replacement Collaborating Group

Registry-linked trialOpen access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Acta orthopaedica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06431906 (TRANSDERMAL FENTANYL AS A FORM OF REBOUND PAIN REDUCTION IN FAST TRACK PROGRAMME IN PRIMARY KNEE ARTHROPLASTY. Prospective Observational Non-inferiority Study Versus Morphine PCA.), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06431906 unknown statusnot on this mapstarted 2024, after this paper: background citation

TRANSDERMAL FENTANYL AS A FORM OF REBOUND PAIN REDUCTION IN FAST TRACK PROGRAMME IN PRIMARY KNEE ARTHROPLASTY. Prospective Observational Non-inferiority Study Versus Morphine PCA.

TypeobservationalSponsorOscar Diaz-CambroneroRan2024 to 2026Enrolled106ConditionsPostoperative Pain
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Martin Lindberg-LarsenOrthopaedic Research Unit, Department of Orthopaedic Surgery and Traumatology, Odense University Hospital; Department of Clinical Research, University of Southern Denmark; Centre for Fast-track Hip and Knee Arthroplasty, Copenhagen, Denmark. martin.lindberg-larsen@rsyd.dk.
Pelle Baggesgaard PetersenSection for Surgical Pathophysiology, Rigshospitalet, Copenhagen, Denmark. pelle.baggesgaard.petersen@regionh.dk.
Yasemin CorapOrthopaedic Research Unit, Department of Orthopaedic Surgery and Traumatology, Odense University Hospital; Department of Clinical Research, University of Southern Denmark. yasemin.corap3@rsyd.dk.
Kirill GromovCentre for Fast-track Hip and Knee Arthroplasty, Copenhagen, Denmark: Department of Orthopedics, Hvidovre Hospital, Hvidovre, Denmark. kirgromov@gmail.com.
Christoffer Calov JørgensenSection for Surgical Pathophysiology, Rigshospitalet, Copenhagen, Denmark. christoffer.calov.joergensen@regionh.dk.
Henrik KehletCentre for Fast-track Hip and Knee Arthroplasty, Copenhagen, Denmark; Section for Surgical Pathophysiology, Rigshospitalet, Copenhagen, Denmark. Henrik.kehlet@regionh.dk.
Centre for Fast-track Hip and Knee Replacement Collaborating Group
Rigshospitalet · DKUniversity of Southern Denmark · DKHvidovre Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeData on application of fasttrack/enhanced recovery protocols in revision hip arthroplasty (R-THA) surgery is scarce. We report length of stay (LOS), risk of LOS > 5 days, and readmission ≤ 90 days after revision hip arthroplasty in centers with a well-established fast-track protocol in both primary and revision procedures. PATIENTS AND

methodsThis is an observational cohort study from the Centre for Fast-track Hip and Knee Replacement and the Danish Hip Arthroplasty Register. Consecutive elective aseptic major component revision hip arthroplasties from 6 dedicated fast-track centers from 2010 to 2018 were included.

results1,345 R-THAs were analyzed, including 23% total revisions, 52% acetabular component revisions, and 25% femoral component revisions. Mean age was 70 years (SD 12) and 61% were female. Median LOS was 3 days (interquartile range [IQR] 2-6), decreasing from median 6 (IQR 3-10) days in 2010 to 2 (IQR 1-4) days in 2018. The 90-day readmission rate was 20%, but showed a fluctuating and increasing trend from 13% in 2010 to 28% in 2018. Risk factors for LOS > 5 days and readmission were use of walking aid, preoperative hemoglobin ≤ 13 g/dL, pharmacological treated psychiatric disorder, age ≥ 80 years, age 70-79 years (only LOS > 5 days), cardiac disease (only LOS > 5 days), pulmonary disease (only readmission), BMI ≥ 35 (only LOS > 5 days) and ≥ 1 previous revision (only LOS > 5 days).

interpretationLOS decreased to median 2 days at the end of the study period, but the 90 days readmission risk remained high (> 20%). Several risk factors for postoperative complications were identified, suggesting that at-risk patients should be treated using an extended fast-track/enhanced recovery protocol focusing on preoperative optimization and postoperative monitoring as well as surgical techniques to reduce hip dislocations.

Indexed as

Arthroplasty, Replacement, HipArthroplasty, Replacement, KneeAgedAged, 80 and overCohort StudiesElective Surgical ProceduresFemaleHumansLength of StayMalePostoperative ComplicationsRisk Factors

Identifiers

PMID35195270
PMCPMC8865005
OpenAlexW4213335436

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.