Evidence map›Paper›PMID 35195229›Full record

ArticleArquivos de neuro-psiquiatria2022

Dysphagia is a strong predictor of death and functional dependence at three months post-stroke.

Aline Cristina Pacheco-Castilho, Rubia Poliana Crisóstomo Miranda, Ana Maria Queirós Norberto, Diandra Bosi Favoretto, Brunna Pileggi Rimoli, Luciana Bezerra de Mello Alves, Karina Tavares Weber, Taiza Elaine Grespan Santos, Julio Cesar Moriguti, João Pereira Leite and 3 more

Open access · goldAbstract read
In one paragraph

Article in Arquivos de neuro-psiquiatria, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Efficacy of transcranial direct current stimulation in patients with dysphagia after stroke: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Pooled it
  3. Multimodal Neural Assessment for Predicting Post-Stroke Dysphagia: Identifying Critical Risk Factors Using Combined Indicators.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Aline Cristina Pacheco-CastilhoUniversidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto SP, Brazil.ORCID 0000-0003-2927-2766
Rubia Poliana Crisóstomo MirandaUniversidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Ribeirão Preto SP, Brazil.ORCID 0000-0001-8670-5308
Ana Maria Queirós NorbertoUniversidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Clínica Médica, Ribeirão Preto SP, Brazil.ORCID 0000-0003-1544-2330
Diandra Bosi FavorettoUniversidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto SP, Brazil.ORCID 0000-0001-6853-1914
Brunna Pileggi RimoliUniversidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto SP, Brazil.ORCID 0000-0001-7434-3127
Luciana Bezerra de Mello AlvesUniversidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto SP, Brazil.ORCID 0000-0002-5068-3677
Karina Tavares WeberUniversidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto SP, Brazil.ORCID 0000-0003-4907-8645
Taiza Elaine Grespan SantosUniversidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto SP, Brazil.ORCID 0000-0003-3033-2981
Julio Cesar MorigutiUniversidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Clínica Médica, Ribeirão Preto SP, Brazil.ORCID 0000-0001-5499-3552
João Pereira LeiteUniversidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto SP, Brazil.ORCID 0000-0003-4240-2393
Roberto Oliveira DantasUniversidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Clínica Médica, Ribeirão Preto SP, Brazil.ORCID 0000-0003-2183-0815
Rosemary MartinoUniversity of Toronto, Graduate Department of Rehabilitation Science, Department of Speech-Language Pathology, Toronto, Ontario, Canada.ORCID 0000-0002-3298-7714
Octávio Marques Pontes-NetoUniversidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Neurociências e Ciências do Comportamento, Ribeirão Preto SP, Brazil.ORCID 0000-0003-0317-843X
Universidade de São Paulo · BRUniversidade de Ribeirão Preto · BRUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFew Brazilian studies investigated risk factors for dysphagia and associated complications in a large cohort.

objectiveTo investigate frequency, predictors, and associated outcomes of dysphagia in patients up to three months post-stroke.

methodsProspective cohort study of consecutively admitted patients in a specialized center for acute stroke. Patients with a transient ischemic attack, subarachnoid hemorrhage, cerebral venous thrombosis, hemorrhagic stroke with secondary cause, non-acute stroke, or those who did not consent to participate were excluded. Swallowing was evaluated by speech language pathologists using Volume-Viscosity Swallow Test. General function at three months post-stroke was assessed using the following instruments: Modified Rankin scale, Barthel Index and Functional Independence Measure.

resultsA total of 831 patients were admitted and 305 patients were included according to the inclusion and exclusion criteria. The mean age of patients was 63.6±13.3 years, mean time from stroke to swallowing assessment was 4.2±4.1 days, and 45.2% of the patients had dysphagia. Age (OR=1.02; 95%CI 1.00-1.04; p=0.017), known medical history of obstructive sleep apnea (OR=5.13; 95%CI 1.74-15.15; p=0.003), and stroke severity at hospital admission (OR=1.10; 95%CI 1.06-1.15; p<0.001) were independently associated with dysphagia. Dysphagia (OR=3.78; 95%CI 2.16-6.61; p<0.001) and stroke severity (OR=1.05; 95%CI 1.00-1.09; p=0.024) were independently associated with death or functional dependence at three months.

conclusionsDysphagia was present in almost half of stroke patients. Age, obstructive sleep apnea, and stroke severity were predictors of dysphagia, which was independently associated with death or functional dependence at three months.

Indexed as

Deglutition DisordersSleep Apnea, ObstructiveStrokeAgedFunctional StatusHumansInfantMiddle AgedProspective Studies

Identifiers

PMID35195229
PMCPMC9238336
OpenAlexW4213387234

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.