Evidence map›Paper›PMID 35195008›Full record

ReviewACS applied bio materials2022

Peptides for Vaccine Development.

Ian W Hamley

Open access · hybridAbstract readReview
In one paragraph

Review in ACS applied bio materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
8.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 100 citations in OpenAlex.

  1. Scorpion Peptides in Antiviral Drug Discovery: An In-depth Review.Probiotics and antimicrobial proteins · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
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  8. Phylogenetic Domain Adaption for Linear B-Cell Epitope Prediction.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
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  15. Article
  16. Design of a Multi-Epitope Vaccine Based onInternational journal of molecular sciences · 2025
    Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Ian W HamleyDepartment of Chemistry, University of Reading, Whiteknights, Reading RG6 6AD, U.K.ORCID 0000-0002-4549-0926
University of Reading · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review discusses peptide epitopes used as antigens in the development of vaccines in clinical trials as well as future vaccine candidates. It covers peptides used in potential immunotherapies for infectious diseases including SARS-CoV-2, influenza, hepatitis B and C, HIV, malaria, and others. In addition, peptides for cancer vaccines that target examples of overexpressed proteins are summarized, including human epidermal growth factor receptor 2 (HER-2), mucin 1 (MUC1), folate receptor, and others. The uses of peptides to target cancers caused by infective agents, for example, cervical cancer caused by human papilloma virus (HPV), are also discussed. This review also provides an overview of model peptide epitopes used to stimulate non-specific immune responses, and of self-adjuvanting peptides, as well as the influence of other adjuvants on peptide formulations. As highlighted in this review, several peptide immunotherapies are in advanced clinical trials as vaccines, and there is great potential for future therapies due the specificity of the response that can be achieved using peptide epitopes.

Indexed as

Vaccine DevelopmentAdjuvants, ImmunologicAnimalsAntigensCancer VaccinesCommunicable Disease ControlHumansNeoplasmsPeptidesVaccines, SubunitAdjuvants, ImmunologicAntigensCancer VaccinesPeptidesVaccines, Subunitadjuvantscancerepitopesimmune responseinfectious diseasesPeptidesvaccines

Identifiers

PMID35195008
PMCPMC9384901
OpenAlexW4213428209

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.