Evidence map›Paper›PMID 35194698›Full record

Trial reportAIDS and behavior2022

Efficacy of a Telehealth Delivered Couples' HIV Counseling and Testing (CHTC) Intervention to Improve Formation and Adherence to Safer Sexual Agreements Among Male Couples in the US: Results from a Randomized Control Trial.

Rob Stephenson, Stephen P Sullivan, Jason W Mitchell, Brent A Johnson, Patrick S Sullvian

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 4 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Review
  7. Article
  8. Article
  9. A Narrative Study of Sexual Agreements and HIV Prevention Strategies Among Emerging Adult Sexual Minority Men.Prevention science : the official journal of the Society for Prevention Research · 2025
    Article
  10. Couples Have a Way of Speaking: Examining the Characteristics and Stability of Communication Style in HIV Testing Sessions With Male Couples.AIDS education and prevention : official publication of the International Society for AIDS Education · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Leveraging mHealth for the Treatment and Management of PLHIV.Risk management and healthcare policy · 2023
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Rob StephensonThe Center for Sexuality and Health Disparities, Department of Systems, Populations and Leadership, School of Nursing, University of Michigan, 400 N Ingalls Street, Ann Arbor, MI, 48109, USA. rbsteph@umich.edu.ORCID http://orcid.org/0000-0002-9239-2640
Stephen P SullivanThe Center for Sexuality and Health Disparities, Department of Systems, Populations and Leadership, School of Nursing, University of Michigan, 400 N Ingalls Street, Ann Arbor, MI, 48109, USA.
Jason W MitchellDepartment of Health Promotion and Disease Prevention, Stempel College of Public Health and Social Work, Florida International University, Miami, FL, USA.
Brent A JohnsonDepartment of Biostatistics and Computional Biology, University of Rochestor Medical Center, Rochester, NY, USA.
Patrick S SullvianDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
University of Michigan · USEmory University · USFlorida International University · USUniversity of Rochester Medical Center · US

Funding

Providing online counseling for home-based HIV testing.R01HD078131 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI STEPHENSON, ROB B. · 2014 to 2017
$2.7M
NICHD NIH HHS R01 HD078131
6 · The paper itself

Abstract

This paper reports the results of a randomized controlled trial (RCT) to assess the efficacy of Nexus, a telehealth delivered intervention that combines Couples' HIV counseling and testing (CHTC) with home-based HIV-testing, examining the impact of the intervention on the couples' formation and adherence to safer sexual agreements. Between 2016 and 2018, 424 couples were recruited online from the U.S and randomized to the intervention arm (a telehealth delivered CHTC session with two home HIV-testing kits) or a control arm (two home HIV-testing kits), with study assessments at baseline, 3 and 6 months. Outcomes were the formation and adherence to safer sexual agreements, dyadic discordance in sexual agreements, breakage of sexual agreements, and perceptions of PrEP. Couples in the intervention arm had significantly greater odds of reporting a safer sexual agreement (3 months OR 1.87, p-value 0.005, and 6 months OR 1.84, p-value 0.007), lower odds of reporting discordant sexual agreements at 6 months (OR 0.62, p-value 0.048), and a significantly lower odds of reporting breaking their sexual agreement (3 months OR 0.51, p-value 0.035, and 6 months OR 0.23, p-value 0.000). By 6 months, couples in the intervention arm were less likely to say PrEP was beneficial to one (RRR 0.33, P = 0.000) or both of them (RRR 0.29, P = 0.000) than being beneficial to neither of the partners. The high levels of acceptability and efficacy of the intervention demonstrate strong potential for the scale-up of this efficacious intervention that is delivered through a low-cost telehealth platform.

Indexed as

HIV InfectionsTelemedicineChitinasesCounselingHumansMalePlant ProteinsSexual Partnerschitinase CChitinasesPlant ProteinsHIV preventionMale couplesRCTRisk reductionSexual agreementsTelehealth

Identifiers

PMID35194698
PMCPMC8863094
OpenAlexW4213428597

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.