Evidence map›Paper›PMID 35194441›Full record

ArticleIranian journal of pharmaceutical research : IJPR2021

Development and Optimization of Lipid-polymer Hybrid Nanoparticles Containing Melphalan Using Central Composite Design and Its Effect on Ovarian Cancer Cell Lines.

Seyedeh Masoomeh Sadat Mirnezami, Amir Heydarinasab, Azim Akbarzadehkhyavi, Mehdi Adrjmand

Open access · greenAbstract read
In one paragraph

Article in Iranian journal of pharmaceutical research : IJPR, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Seyedeh Masoomeh Sadat MirnezamiDepartment of Chemical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran .
Amir HeydarinasabDepartment of Chemical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran .
Azim AkbarzadehkhyaviDepartment of Pilot Nano-biotechnology, Pasteur Institute of Iran, Tehran, Iran.
Mehdi AdrjmandDepartment of Chemical Engineering, South Tehran Branch, Islamic Azad University, Tehran, Iran.
Islamic Azad University South Tehran Branch · IRPasteur Institute of Iran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of controlled-release drug delivery systems has a great potential to improve the efficacy of anticancer drugs. This study aimed to develop and optimize the production of hybrid lipid-polymer nanoparticles (

Indexed as

Central Composite DesignHLPNPsMelphalanMTT assayNanoprecipitationovarian cancer

Identifiers

PMID35194441
PMCPMC8842616
OpenAlexW3170076463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.