ArticleBDJ open2022
Up to 7% of referrals to oral and maxillofacial surgery are related to medication-related osteonecrosis of the jaws: how much is really out there?
Article in BDJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
Funding
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Abstract
introductionMedication-related osteonecrosis of the jaws (MRONJ) is generally described as rare; therefore, firm incidence data are challenging to ascertain.
aimUsing two sites in Northwest England, ascertain the number of referrals to oral and maxillofacial surgery involving: Suspected MRONJ. Patients at risk of MRONJ requiring a dentoalveolar procedure.
methodAll sequential referrals over a 2-year period were analysed. The referrals were categorised into 'type' of referral (stage 1). Any referral for MRONJ, or patient at risk, was then further examined (stage 2).
resultsA total of 2150 referrals were screened. The most common referral reasons were temporomandibular joint issues and hard tissue conditions. The proportion of referrals for suspected MRONJ was similar for both sites: 3.7% (site 1) and 3.4% (site 2). At site 1, 1.6% of all referrals were at risk of MRONJ referred for treatment. In site 2, 3.8% of all referrals were in this category.
conclusionDespite limitations, the finding that patients with or at risk of MRONJ potentially equates to 7% of all referrals represents a substantial proportion of OMFS practice. Therefore, there are clear benefits of collecting accurate data prospectively to understand the scale of this condition and its impact on services.
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