Evidence map›Paper›PMID 35193878›Full record

Observational studyCMAJ open

SARS-CoV-2 outbreak in a Canadian suburban tertiary hospital necessitating full facility closure: a descriptive observational study.

Jamil N Kanji, Y L Elaine Chan, Lesia R Boychuk, Curtiss Boyington, Sebora Turay, Melissa Kobelsky, Carolyn Doroshuk, Philana Choo, Susan Jacka, Erin Roberts and 4 more

Open access · diamondAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Jamil N KanjiDivision of Infectious Diseases, Department of Medicine (Kanji, Boychuk, Boyington, Smith), University of Alberta; Covenant Health (Kanji, Boychuk, Boyington, Turay, Kobelsky, Doroshuk, Choo, Jacka, Roberts, Leighton, Black); Canadian Public Health Service, Public Health Agency of Canada (Chan); Division of Preventive Medicine, Faculty of Medicine and Dentistry (Sikora), University of Alberta; Medical Officer of Health (Edmonton Zone), (Sikora) Alberta Health Services; Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry (Black), University of Alberta, Edmonton, Alta. Note: Dr. J.N. Kanji is now with the Division of Infectious Diseases, Department of Medicine and Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alta. jamil.kanji@ahs.ca.
Y L Elaine ChanDivision of Infectious Diseases, Department of Medicine (Kanji, Boychuk, Boyington, Smith), University of Alberta; Covenant Health (Kanji, Boychuk, Boyington, Turay, Kobelsky, Doroshuk, Choo, Jacka, Roberts, Leighton, Black); Canadian Public Health Service, Public Health Agency of Canada (Chan); Division of Preventive Medicine, Faculty of Medicine and Dentistry (Sikora), University of Alberta; Medical Officer of Health (Edmonton Zone), (Sikora) Alberta Health Services; Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry (Black), University of Alberta, Edmonton, Alta. Note: Dr. J.N. Kanji is now with the Division of Infectious Diseases, Department of Medicine and Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alta.
Lesia R BoychukDivision of Infectious Diseases, Department of Medicine (Kanji, Boychuk, Boyington, Smith), University of Alberta; Covenant Health (Kanji, Boychuk, Boyington, Turay, Kobelsky, Doroshuk, Choo, Jacka, Roberts, Leighton, Black); Canadian Public Health Service, Public Health Agency of Canada (Chan); Division of Preventive Medicine, Faculty of Medicine and Dentistry (Sikora), University of Alberta; Medical Officer of Health (Edmonton Zone), (Sikora) Alberta Health Services; Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry (Black), University of Alberta, Edmonton, Alta. Note: Dr. J.N. Kanji is now with the Division of Infectious Diseases, Department of Medicine and Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alta.
Curtiss BoyingtonDivision of Infectious Diseases, Department of Medicine (Kanji, Boychuk, Boyington, Smith), University of Alberta; Covenant Health (Kanji, Boychuk, Boyington, Turay, Kobelsky, Doroshuk, Choo, Jacka, Roberts, Leighton, Black); Canadian Public Health Service, Public Health Agency of Canada (Chan); Division of Preventive Medicine, Faculty of Medicine and Dentistry (Sikora), University of Alberta; Medical Officer of Health (Edmonton Zone), (Sikora) Alberta Health Services; Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry (Black), University of Alberta, Edmonton, Alta. Note: Dr. J.N. Kanji is now with the Division of Infectious Diseases, Department of Medicine and Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alta.
Sebora TurayDivision of Infectious Diseases, Department of Medicine (Kanji, Boychuk, Boyington, Smith), University of Alberta; Covenant Health (Kanji, Boychuk, Boyington, Turay, Kobelsky, Doroshuk, Choo, Jacka, Roberts, Leighton, Black); Canadian Public Health Service, Public Health Agency of Canada (Chan); Division of Preventive Medicine, Faculty of Medicine and Dentistry (Sikora), University of Alberta; Medical Officer of Health (Edmonton Zone), (Sikora) Alberta Health Services; Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry (Black), University of Alberta, Edmonton, Alta. Note: Dr. J.N. Kanji is now with the Division of Infectious Diseases, Department of Medicine and Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alta.
Melissa KobelskyDivision of Infectious Diseases, Department of Medicine (Kanji, Boychuk, Boyington, Smith), University of Alberta; Covenant Health (Kanji, Boychuk, Boyington, Turay, Kobelsky, Doroshuk, Choo, Jacka, Roberts, Leighton, Black); Canadian Public Health Service, Public Health Agency of Canada (Chan); Division of Preventive Medicine, Faculty of Medicine and Dentistry (Sikora), University of Alberta; Medical Officer of Health (Edmonton Zone), (Sikora) Alberta Health Services; Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry (Black), University of Alberta, Edmonton, Alta. Note: Dr. J.N. Kanji is now with the Division of Infectious Diseases, Department of Medicine and Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alta.
Carolyn DoroshukDivision of Infectious Diseases, Department of Medicine (Kanji, Boychuk, Boyington, Smith), University of Alberta; Covenant Health (Kanji, Boychuk, Boyington, Turay, Kobelsky, Doroshuk, Choo, Jacka, Roberts, Leighton, Black); Canadian Public Health Service, Public Health Agency of Canada (Chan); Division of Preventive Medicine, Faculty of Medicine and Dentistry (Sikora), University of Alberta; Medical Officer of Health (Edmonton Zone), (Sikora) Alberta Health Services; Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry (Black), University of Alberta, Edmonton, Alta. Note: Dr. J.N. Kanji is now with the Division of Infectious Diseases, Department of Medicine and Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alta.
Philana ChooDivision of Infectious Diseases, Department of Medicine (Kanji, Boychuk, Boyington, Smith), University of Alberta; Covenant Health (Kanji, Boychuk, Boyington, Turay, Kobelsky, Doroshuk, Choo, Jacka, Roberts, Leighton, Black); Canadian Public Health Service, Public Health Agency of Canada (Chan); Division of Preventive Medicine, Faculty of Medicine and Dentistry (Sikora), University of Alberta; Medical Officer of Health (Edmonton Zone), (Sikora) Alberta Health Services; Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry (Black), University of Alberta, Edmonton, Alta. Note: Dr. J.N. Kanji is now with the Division of Infectious Diseases, Department of Medicine and Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alta.
Susan JackaDivision of Infectious Diseases, Department of Medicine (Kanji, Boychuk, Boyington, Smith), University of Alberta; Covenant Health (Kanji, Boychuk, Boyington, Turay, Kobelsky, Doroshuk, Choo, Jacka, Roberts, Leighton, Black); Canadian Public Health Service, Public Health Agency of Canada (Chan); Division of Preventive Medicine, Faculty of Medicine and Dentistry (Sikora), University of Alberta; Medical Officer of Health (Edmonton Zone), (Sikora) Alberta Health Services; Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry (Black), University of Alberta, Edmonton, Alta. Note: Dr. J.N. Kanji is now with the Division of Infectious Diseases, Department of Medicine and Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alta.
Erin RobertsDivision of Infectious Diseases, Department of Medicine (Kanji, Boychuk, Boyington, Smith), University of Alberta; Covenant Health (Kanji, Boychuk, Boyington, Turay, Kobelsky, Doroshuk, Choo, Jacka, Roberts, Leighton, Black); Canadian Public Health Service, Public Health Agency of Canada (Chan); Division of Preventive Medicine, Faculty of Medicine and Dentistry (Sikora), University of Alberta; Medical Officer of Health (Edmonton Zone), (Sikora) Alberta Health Services; Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry (Black), University of Alberta, Edmonton, Alta. Note: Dr. J.N. Kanji is now with the Division of Infectious Diseases, Department of Medicine and Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alta.
Karen LeightonDivision of Infectious Diseases, Department of Medicine (Kanji, Boychuk, Boyington, Smith), University of Alberta; Covenant Health (Kanji, Boychuk, Boyington, Turay, Kobelsky, Doroshuk, Choo, Jacka, Roberts, Leighton, Black); Canadian Public Health Service, Public Health Agency of Canada (Chan); Division of Preventive Medicine, Faculty of Medicine and Dentistry (Sikora), University of Alberta; Medical Officer of Health (Edmonton Zone), (Sikora) Alberta Health Services; Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry (Black), University of Alberta, Edmonton, Alta. Note: Dr. J.N. Kanji is now with the Division of Infectious Diseases, Department of Medicine and Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alta.
Stephanie W SmithDivision of Infectious Diseases, Department of Medicine (Kanji, Boychuk, Boyington, Smith), University of Alberta; Covenant Health (Kanji, Boychuk, Boyington, Turay, Kobelsky, Doroshuk, Choo, Jacka, Roberts, Leighton, Black); Canadian Public Health Service, Public Health Agency of Canada (Chan); Division of Preventive Medicine, Faculty of Medicine and Dentistry (Sikora), University of Alberta; Medical Officer of Health (Edmonton Zone), (Sikora) Alberta Health Services; Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry (Black), University of Alberta, Edmonton, Alta. Note: Dr. J.N. Kanji is now with the Division of Infectious Diseases, Department of Medicine and Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alta.
Christopher SikoraDivision of Infectious Diseases, Department of Medicine (Kanji, Boychuk, Boyington, Smith), University of Alberta; Covenant Health (Kanji, Boychuk, Boyington, Turay, Kobelsky, Doroshuk, Choo, Jacka, Roberts, Leighton, Black); Canadian Public Health Service, Public Health Agency of Canada (Chan); Division of Preventive Medicine, Faculty of Medicine and Dentistry (Sikora), University of Alberta; Medical Officer of Health (Edmonton Zone), (Sikora) Alberta Health Services; Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry (Black), University of Alberta, Edmonton, Alta. Note: Dr. J.N. Kanji is now with the Division of Infectious Diseases, Department of Medicine and Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alta.
Robert BlackDivision of Infectious Diseases, Department of Medicine (Kanji, Boychuk, Boyington, Smith), University of Alberta; Covenant Health (Kanji, Boychuk, Boyington, Turay, Kobelsky, Doroshuk, Choo, Jacka, Roberts, Leighton, Black); Canadian Public Health Service, Public Health Agency of Canada (Chan); Division of Preventive Medicine, Faculty of Medicine and Dentistry (Sikora), University of Alberta; Medical Officer of Health (Edmonton Zone), (Sikora) Alberta Health Services; Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry (Black), University of Alberta, Edmonton, Alta. Note: Dr. J.N. Kanji is now with the Division of Infectious Diseases, Department of Medicine and Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alta.
Public Health Agency of Canada · CAAlberta Health Services · CAUniversity of Alberta · CACovenant Health · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSARS-CoV-2 can cause outbreaks in community- and hospital-based settings. The aim of this study was to provide a detailed epidemiologic account of a hospital-wide SARS-CoV-2 outbreak and provide a description of case evaluations, transmission networks and the interventions implemented to stem the outbreak.

methodsWe conducted a retrospective descriptive study of a hospital-wide SARS-CoV-2 outbreak at the Misericordia Community Hospital (Edmonton) from June 21 to Aug. 14, 2020. We reviewed hospital chart, public health and occupational health records to determine demographics, case type (community- or hospital-acquired), need for critical care and outcome for each case linked to the outbreak (patients, hospital staff, and community and patient visitors). We developed detailed transmission networks using epidemiologic data to determine what variables may have contributed to transmission.

resultsFifty-eight cases of SARS-CoV-2 infection were linked to this hospital outbreak (31 patients, 25 staff members and 2 visitors; 66% female, age range 19-97 years). One patient required critical care, and 11 deaths were recorded (all among inpatients). Most cases were hospital-acquired (91%), and 28% were asymptomatic at the time of diagnosis. The outbreak was composed of 2 clusters driven by protective equipment breaches, premature removal of precautions, transmission in small staff quarters and infection of a staff member after exposure to a wandering patient with dementia and asymptomatic, undetected SARS-CoV-2 infection.

interpretationA detailed epidemiologic review of this hospital-wide outbreak shows that a SARS-CoV-2 outbreak can involve complex transmission chains and clusters. Multipronged bundled approaches, aggressive contact tracing, and patient and staff prevalence screening are important to help bring such outbreaks under control, along with ongoing vigilance in detecting delayed cases.

Indexed as

Disease OutbreaksSARS-CoV-2Tertiary Care CentersCanadaContact TracingCOVID-19Cross InfectionFemaleHealth PersonnelHospitals, CommunityHumansMalePrevalencePublic Health SurveillanceRetrospective Studies

Identifiers

PMID35193878
PMCPMC9259436
OpenAlexW4213374772

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.