ReviewThe journal of international advanced otology2022
Benign Paroxysmal Positional Vertigo: Is It Really an Otolith Disease?
Review in The journal of international advanced otology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Identifying key risk factors for the recurrence of benign paroxysmal positional vertigo following successful canalith repositioning maneuvers: a meta analysis.European journal of medical research · 2025Pooled it
- Risk of Benign Paroxysmal Positional Vertigo Modified by Diuretics-A Population-Level Case-Control Study.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Article
- Variations in the Diagnosis and Management of Benign Paroxysmal Positional Vertigo Among Physician Specialties in Saudi Arabia: Influence of Clinical Experience and Case Exposure.Healthcare (Basel, Switzerland) · 2025Article
- Effect of different maneuvers of repositioning on benign paroxysmal vertigo: a network meta-analysis.BMC neurology · 2025Article
- Effect of canalith repositioning on resting-state brain functional connectivity in patients with benign paroxysmal positional vertigo.Frontiers in neurology · 2025Article
- Observational
- Clinical characteristics and caloric testing in patients with light or heavy cupula of the horizontal semicircular canal.Frontiers in neurology · 2025Article
- A minimal ion-chemistry model for predicting benign paroxysmal positional vertigo risk based on endolymphatic calcium and pH.Frontiers in neurology · 2025Article
- Transcriptomic analysis reveals cross-talk genes between type 2 diabetes and recurrent benign paroxysmal positional vertigo.Heliyon · 2024Article
- Understanding Benign Paroxysmal Positional Vertigo (BPPV) and Its Impact on Quality of Life: A Systematic Review.Cureus · 2024Review
- Review
- Associations between benign paroxysmal positional vertigo and seven mental disorders: a two-sample Mendelian randomization study.Frontiers in neurology · 2024Article
- Management of Migraine-Associated Vestibulocochlear Disorders.Audiology research · 2023Review
- Serum neurotransmitter imbalances in benign paroxysmal positional vertigo: correlations with anxiety, depression, and sleep quality.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current theory in physiopathology of benign paroxysmal positional vertigo is the mechanical theory, namely the cupulolithiasis-canalolithiasis theory. Repositioning maneuvers based on this theory has now taken place in therapy. However, mechanical theory is insufficient to explain some clinical situations and cannot fully enlighten the physiopathology. Mechanical theory is based on very few histological studies. Currently, these few articles are still used for reference. Anatomically, there are uncertainties that need to be explained in this theory. In this literature review, the histological and anatomical evidence is reviewed and the value of mechanical theory in benign paroxysmal positional vertigo physiopathology has been questioned. Studies suggest that the debris in the semicircular canals is caused by degeneration due to aging and may not be responsible for the symptoms in benign paroxysmal positional vertigo. Some patients with debris in semicircular canals do not have benign paroxysmal positional vertigo symptomatology, while some patients without debris may have benign paroxysmal positional vertigo symptomatology. Experimental and histological findings suggest that vestibulopathy due to inflammation caused by neurotropic viruses may lead to benign paroxysmal positional vertigo picture. For all these reasons, in benign paroxysmal positional vertigo physiopathology, there must be other factors besides particle debris in semicircular canals.
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Registered trials
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