Evidence map›Paper›PMID 35193841›Full record

ArticleThe journal of international advanced otology2022

A Different Era for Malignant Otitis Externa: The Non-Diabetic and Non-Immunocompromised Patients.

Giorgos Sideris, John Latzonis, Caroline Avgeri, Vangelis Malamas, Alexander Delides, Thomas Nikolopoulos

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of international advanced otology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Malignant otitis externa: What is the role of surgery?Laryngoscope investigative otolaryngology · 2024
    Article
  3. Review
  4. Article
  5. Malignant External Otitis: What the Diabetes Specialist Should Know-A Narrative Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Giorgos Sideris2nd Otolaryngology Department, National and Kapodistrian University of Athens Faculty of Medicine, "Attikon" University Hospital, Athens, Greece.
John Latzonis2nd Otolaryngology Department, National and Kapodistrian University of Athens Faculty of Medicine, "Attikon" University Hospital, Athens, Greece.
Caroline Avgeri2nd Otolaryngology Department, National and Kapodistrian University of Athens Faculty of Medicine, "Attikon" University Hospital, Athens, Greece.
Vangelis MalamasDepartment of Informatics, University of Piraeus, Piraeus, Greece.
Alexander Delides2nd Otolaryngology Department, National and Kapodistrian University of Athens Faculty of Medicine, "Attikon" University Hospital, Athens, Greece.
Thomas Nikolopoulos2nd Otolaryngology Department, National and Kapodistrian University of Athens Faculty of Medicine, "Attikon" University Hospital, Athens, Greece.
National and Kapodistrian University of Athens · GRUniversity of Piraeus · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundΤo investigate the differences in regard to the clinical, laboratory, and imaging findings as well as the treatment course between diabetic and non-diabetic, non-immunocompromised patients with malignant otitis externa.

methodsA total of 36 hospitalized patients diagnosed with malignant otitis externa between January 2011 and December 2020 were divided into 2 groups according to their medical history, blood glucose, and glycated hemoglobin levels.

resultsThirty-two patients were diabetic (group A) and 4 were non-diabetic, non-immunocompromised (group B). Otalgia was present in all patients (100%), followed by otorrhoea (67%) and edema (64%). Polyps were present in 18 patients (50%). Pseudomonas aeruginosa was isolated in 16 out of 25 positive cultures (64%). Four patients of group A and none of group B underwent surgery. Five patients of group A and none of group B had at least 1 cranial nerve involvement. The mean age was 77.22 ± 8.17 for group A and 47.25 ± 3.59 for group B (P < .001). No statistical significance was observed in regards to major symptoms, inflammatory markers (white blood cell, C-reactive protein, and erythrocyte sedimentation rate), positive imaging, and microbiological findings between the 2 groups. The average days of hospitalization were 42.41 ± 31.06 for group A and 10.25 ± 2.63 for group B (P < .049). Four diabetic patients died.

conclusionNon-diabetic, non-immunocompromised adult patients with malignant otitis externa had a better response to antibiotic therapy and a shorter length of hospitalization. A high clinical suspicion for malignant otitis externa should always raise in cases of otitis externa that fail to respond in a topic and/or oral antibiotic treatment for more than a week.

Indexed as

Otitis ExternaAgedAged, 80 and overAnti-Bacterial AgentsHumansPseudomonas aeruginosaAnti-Bacterial Agents

Identifiers

PMID35193841
PMCPMC9449702
OpenAlexW4210442582

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.